PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29705383-8	2018	Flow cytometric analysis showed that endosulfan at 50 and 75 muM induced cell cycle G1 arrest, a response attributed to down-regulation of CDK6 and up-regulation of p21.	Endosulfan	37-47	H3 histone pseudogene 16	Homo sapiens	165-168	
27939630-3	2017	We also found that endosulfan can damage microfilaments, microtubules, and nuclei; arrest mitosis; remarkably increase the expressions of Dll4, Notch1, Cleaved-Notch1, Jagged1, Notch4, Hes1, and p21; and significantly induce ROS and malondialdehyde production in HUVECs.	Endosulfan	19-29	H3 histone pseudogene 16	Homo sapiens	195-198	
34856488-5	2021	The results showed that endosulfan significantly promoted cell proliferation, accompanied with the decrease of p27 mRNA expression and the increase in the mRNA expression levels of p21 and inflammatory factors IL-6/IL-8.	Endosulfan	24-34	H3 histone pseudogene 16	Homo sapiens	181-184