PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32000066-0	2020	Scoparone improves hepatic inflammation and autophagy in mice with nonalcoholic steatohepatitis by regulating the ROS/P38/Nrf2 axis and PI3K/AKT/mTOR pathway in macrophages.	scoparone	0-9	thymoma viral proto-oncogene 1	Mus musculus	141-144	
32000066-11	2020	In addition, scoparone suppressed activation of the PI3K/AKT/mTOR pathway, and MHY1485 (an mTOR activator that inhibits autophagy) inhibited the anti-inflammatory effect of scoparone.	scoparone	13-22	thymoma viral proto-oncogene 1	Mus musculus	57-60	
32000066-11	2020	In addition, scoparone suppressed activation of the PI3K/AKT/mTOR pathway, and MHY1485 (an mTOR activator that inhibits autophagy) inhibited the anti-inflammatory effect of scoparone.	scoparone	173-182	thymoma viral proto-oncogene 1	Mus musculus	57-60	
32000066-12	2020	CONCLUSIONS: In LPS-induced macrophages, scoparone regulates autophagy and further suppresses inflammation by inhibiting the ROS/P38/Nrf2 axis and PI3K/AKT/mTOR pathway and enhancing autophagic flux.	scoparone	41-50	thymoma viral proto-oncogene 1	Mus musculus	152-155	
29793313-9	2018	In addition, phosphoinositide 3-kinase/protein kinase B (PI3K/AKT) pathway in Pilo-induced acute seizures was also inactivated by scoparone.	scoparone	130-139	thymoma viral proto-oncogene 1	Mus musculus	62-65	
29793313-10	2018	In vitro, we confirmed that scoparone inhibited LPS-caused astrocytes activation as proved by the reduced glial fibrillary acidic protein (GFAP) levels, inflammation and apoptosis, which were at least partly dependent on AKT suppression.	scoparone	28-37	thymoma viral proto-oncogene 1	Mus musculus	221-224