PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29420790-6 2018 By contrast, the mre11 mutations restoring sae2Delta resistance only to phleomycin are located in Mre11 C-terminus and bypass Sae2 function in end-tethering but not in DSB resection, possibly by destabilizing the Mre11-Rad50 open conformation. sae2delta 43-52 RAD50 double strand break repair protein Homo sapiens 219-224