PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33292347-10	2020	In addition, catechins could significantly down-regulated the expression of p-NF-kappaB p65 in the uterus and the protein expressions of the pro-inflammatory factors (IL-1beta, IL-6, and TNF-alpha).	Catechin	13-22	interleukin 6	Mus musculus	177-181	
12673036-3	2003	(+)-Catechin caused a significant elevation of cell survival at 10(-5) and 10(-4) M and alkaline phosphatase activity at 10(-5) M. Also, treatment with (+)-catechin (10(-5) M) decreased bone-resorbing cytokines (TNF-alpha and IL-6) production and apoptosis in osteoblasts.	Catechin	0-12	interleukin 6	Mus musculus	226-230	
31007758-2	2019	The present study was undertaken to determine the suppressive effects of (+)-catechin, baicalin or beta-caryophyllene on the production of inflammatory cytokines, including TNF-alpha, IL-6 and IL-1beta, which was enhanced by lipopolysaccharide (LPS) in RAW264.7 cells in vitro.	Catechin	73-85	interleukin 6	Mus musculus	184-188	
26878122-11	2016	TNF-alpha, IL-6, NO, MPO and MDA were reduced in the mice administered epicatechin, whereas antioxidant enzymes showed increased activity in epicatechin-treated mice and cell line respectively.	Catechin	71-82	interleukin 6	Mus musculus	11-15	
26227399-4	2015	Additionally, (+)-catechin suppressed the production of tumor necrosis factor-alpha (TNF-alpha) and interleukin (IL)-6, while augmenting IL-4.	Catechin	14-26	interleukin 6	Mus musculus	100-118	
21498061-8	2011	Moreover GTP and its bioactive components (catechin, epigallocatechin and epigallocatechin-3-gallate) assisted in decreasing the leukocytopenia seen after whole mice irradiation and significantly reduced the elevated serum inflammatory cytokines (TNF-alpha, IL-1beta, and IL-6).	Catechin	43-51	interleukin 6	Mus musculus	272-276	
26234731-5	2015	Subcutaneous injection of gallic acid or catechin significantly reduced MSU-induced IL-1beta and IL-6 secretion in C57BL/6 mice.	Catechin	41-49	interleukin 6	Mus musculus	97-101	
25004880-13	2014	Besides, the mRNAs and levels of IL-6 and TNF-alpha also decreased by quercetin and catechin treatment in LPS-induced RAW264.7 cells.	Catechin	84-92	interleukin 6	Mus musculus	33-37	
15491098-1	2004	AIM: To study the effect of catechin, the active component of Spatholobus suberectus Dunn, on bone marrow cell cycle and the expression of IL-6 and GM-CSF mRNA in spleen cells of normal and marrow-depressed mice in order to clarify the mechanism of hematopoietic-supportive effect of catechin.	Catechin	28-36	interleukin 6	Mus musculus	139-143	
15491098-2	2004	METHODS: Flow cytometry was adopted to investigate the influence of catechin on bone marrow cell cycle in mice and the expression of IL-6 and GM-CSF mRNA induced by catechin in spleen cells was detected by RT-PCR technique simultaneously.	Catechin	68-76	interleukin 6	Mus musculus	133-137	
15491098-2	2004	METHODS: Flow cytometry was adopted to investigate the influence of catechin on bone marrow cell cycle in mice and the expression of IL-6 and GM-CSF mRNA induced by catechin in spleen cells was detected by RT-PCR technique simultaneously.	Catechin	165-173	interleukin 6	Mus musculus	133-137	
15491098-4	2004	Being induced by catechin, IL-6 mRNA and GM-CSF mRNA in spleen cells were markedly up-regulated.	Catechin	17-25	interleukin 6	Mus musculus	27-31	
12673036-3	2003	(+)-Catechin caused a significant elevation of cell survival at 10(-5) and 10(-4) M and alkaline phosphatase activity at 10(-5) M. Also, treatment with (+)-catechin (10(-5) M) decreased bone-resorbing cytokines (TNF-alpha and IL-6) production and apoptosis in osteoblasts.	Catechin	152-164	interleukin 6	Mus musculus	226-230