PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33850236-0	2021	Author Correction: Catechin and curcumin interact with S protein of SARS-CoV2 and ACE2 of human cell membrane: insights from computational studies.	Catechin	19-27	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	55-56	
33302853-0	2021	Silybin B and Cianidanol Inhibit M pro and Spike Protein of SARS-CoV-2: Evidence from in Silico Molecular Docking Studies.	Catechin	14-24	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	43-48	
33386025-5	2021	Further, the molecular interactions determined by molecular dynamics simulation revealed that among the 75 drug molecules, catechin can effectively bind to 3CLpro, CTSL, RBD of S protein, NSP6 and nucleocapsid protein.	Catechin	123-131	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	166-167	
32770567-6	2021	In the current study we demonstrated by bioinformatics (CASTp: computed atlas of surface topography of protein, PyMol: molecular visualization) and molecular docking (PatchDock and Autodock) experiments that tea flavonoids catechin products mainly epigallocatechin gallate or other like theaflavin gallate demonstrated higher atomic contact energy (ACE) value, binding energy, Ki value, ligand efficiency, surface area and more amino acid interactions than hydroxychloroquine (HCQ) during binding in the central channel of the spike protein.	Catechin	223-231	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	527-532	
33479401-0	2021	Catechin and curcumin interact with S protein of SARS-CoV2 and ACE2 of human cell membrane: insights from computational studies.	Catechin	0-8	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	36-37	
33479401-4	2021	It is evident from the present computational study, that catechin and curcumin, not only exhibit strong binding affinity to viral S Protein and host receptor ACE2 but also to their complex (receptor-binding domain (RBD) of the spike protein of SARS-CoV2 and ACE2; RBD/ACE2-complex).	Catechin	57-65	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	130-131	
33479401-4	2021	It is evident from the present computational study, that catechin and curcumin, not only exhibit strong binding affinity to viral S Protein and host receptor ACE2 but also to their complex (receptor-binding domain (RBD) of the spike protein of SARS-CoV2 and ACE2; RBD/ACE2-complex).	Catechin	57-65	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	227-232	
33479401-8	2021	Contrary to this, catechin binds with amino acid residues present near the RBD site of S Protein and causes fluctuation in the amino acid residues of the RBD and its near proximity.	Catechin	18-26	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	87-88	
33479401-10	2021	Protein-protein interaction studies in presence of curcumin or catechin also corroborate the above findings suggesting the efficacy of these two polyphenols in hindering the formation of S Protein-ACE2 complex.	Catechin	63-71	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	187-188	
33479401-5	2021	The binding affinity values of catechin and curcumin for the S protein, ACE2 and RBD/ACE2-complex are - 10.5 and - 7.9 kcal/mol; - 8.9 and - 7.8 kcal/mol; and - 9.1 and - 7.6 kcal/mol, respectively.	Catechin	31-39	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	61-62	
34147855-9	2021	METHOD: In this study, we performed molecular docking of different catechins with the wild and mutant variants of the spike protein of SARS-CoV-2.	Catechin	67-76	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	118-123	
34147855-11	2021	RESULTS: The in-silico studies show that the catechins form favourable interactions with the spike protein and can potentially impair its function.	Catechin	45-54	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	93-98