PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30028018-0	2018	The mGluR5 positive allosteric modulator VU0409551 improves synaptic plasticity and memory of a mouse model of Huntington"s disease.	VU0409551	41-50	glutamate receptor, ionotropic, kainate 1	Mus musculus	4-10	
30028018-4	2018	Our results demonstrate that subchronic treatment with the mGluR5 PAM VU0409551 was effective in reversing the memory deficits exhibited by BACHD mice, a mouse model for HD.	VU0409551	70-79	glutamate receptor, ionotropic, kainate 1	Mus musculus	59-65	
30028018-5	2018	Moreover, VU0409551 treatment stabilized mGluR5 at the cellular plasma membrane of BACHD mice, increasing the expression of several genes important for synaptic plasticity, including c-Fos, brain-derived neurotrophic factor, Arc/Arg3.1, syntaxin 1A, and post-synaptic density-95.	VU0409551	10-19	glutamate receptor, ionotropic, kainate 1	Mus musculus	41-47