PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23416050-3 2013 This mechanism utilizes a signaling cascade involving the GTPases Ras1 and Ras2 and protein kinase A, and it culminates in death through the production of toxic reactive oxygen species in a tricarboxylic-acid-cycle- and respiratory-chain-dependent manner. Tricarboxylic Acids 190-208 Ras family GTPase RAS2 Saccharomyces cerevisiae S288C 75-79