PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17615299-1	2007	In Saccharomyces cerevisiae, the initial reaction of the tricarboxylic acid cycle is catalyzed by the mitochondrial citrate synthase Cit1.	Tricarboxylic Acids	57-75	citrate (Si)-synthase CIT1	Saccharomyces cerevisiae S288C	133-137	
10777592-4	2000	We have isolated, in the Saccharomyces cerevisiae gene encoding the tricarboxylic acid cycle enzyme citrate synthase Cit1p, an "assembly mutation," i.e. a mutation that causes a tricarboxylic acid cycle deficiency without affecting the citrate synthase activity.	Tricarboxylic Acids	68-86	citrate (Si)-synthase CIT1	Saccharomyces cerevisiae S288C	117-122	
10777592-4	2000	We have isolated, in the Saccharomyces cerevisiae gene encoding the tricarboxylic acid cycle enzyme citrate synthase Cit1p, an "assembly mutation," i.e. a mutation that causes a tricarboxylic acid cycle deficiency without affecting the citrate synthase activity.	Tricarboxylic Acids	178-196	citrate (Si)-synthase CIT1	Saccharomyces cerevisiae S288C	117-122	
10777592-5	2000	We have shown that a 15-amino acid peptide from wild type Cit1p encompassing the mutation point inhibits the tricarboxylic acid cycle in a dominant manner, and that the inhibitory phenotype is overcome by a co-overexpression of Mdh1p, the mitochondrial malate dehydrogenase.	Tricarboxylic Acids	109-127	citrate (Si)-synthase CIT1	Saccharomyces cerevisiae S288C	58-63	
10777592-6	2000	These data provide the first direct in vivo evidence of interaction between two sequential tricarboxylic acid cycle enzymes, Cit1p and Mdh1p, and indicate that the characterization of assembly mutations by the reversible transdominant inhibition method may be a powerful way to study multienzyme complexes in their physiological context.	Tricarboxylic Acids	91-109	citrate (Si)-synthase CIT1	Saccharomyces cerevisiae S288C	125-130	
7984086-1	1994	The yeast nuclear gene CIT1 encodes mitochondrial citrate synthase, which catalyses the first and rate-limiting step of the tricarboxylic acid (TCA) cycle.	Tricarboxylic Acids	124-142	citrate (Si)-synthase CIT1	Saccharomyces cerevisiae S288C	23-27	
7984086-1	1994	The yeast nuclear gene CIT1 encodes mitochondrial citrate synthase, which catalyses the first and rate-limiting step of the tricarboxylic acid (TCA) cycle.	Tricarboxylic Acids	144-147	citrate (Si)-synthase CIT1	Saccharomyces cerevisiae S288C	23-27	
28076776-5	2017	Among these, Deltaptc7 yeast exhibit an increase in phosphorylation of Cit1p, the canonical citrate synthase of the tricarboxylic acid (TCA) cycle, that diminishes its activity.	Tricarboxylic Acids	116-134	citrate (Si)-synthase CIT1	Saccharomyces cerevisiae S288C	71-76	
28076776-5	2017	Among these, Deltaptc7 yeast exhibit an increase in phosphorylation of Cit1p, the canonical citrate synthase of the tricarboxylic acid (TCA) cycle, that diminishes its activity.	Tricarboxylic Acids	136-139	citrate (Si)-synthase CIT1	Saccharomyces cerevisiae S288C	71-76	
12446845-5	2002	Most of the aneuploid regions were the result of translocations, including three instances of a shared breakpoint on chromosome 14 immediately adjacent to CIT1, which encodes the citrate synthase that performs a key regulated step in the tricarboxylic acid cycle.	Tricarboxylic Acids	238-256	citrate (Si)-synthase CIT1	Saccharomyces cerevisiae S288C	155-159	
10587442-1	1999	Genes CIT1 and CIT2 from Saccharomyces cerevisiae encode mitochondrial and peroxisomal citrate synthases involved in the Krebs tricarboxylic acid (TCA) cycle and glyoxylate pathway, respectively.	Tricarboxylic Acids	127-145	citrate (Si)-synthase CIT1	Saccharomyces cerevisiae S288C	6-10	
10587442-1	1999	Genes CIT1 and CIT2 from Saccharomyces cerevisiae encode mitochondrial and peroxisomal citrate synthases involved in the Krebs tricarboxylic acid (TCA) cycle and glyoxylate pathway, respectively.	Tricarboxylic Acids	147-150	citrate (Si)-synthase CIT1	Saccharomyces cerevisiae S288C	6-10	
10587442-4	1999	A cytosolically localized form of Cit1p was also incompetent for restoration of growth of a Deltacit1 strain on acetate, suggesting that mitochondrial localization of Cit1p is essential for its function in the TCA cycle.	Tricarboxylic Acids	210-213	citrate (Si)-synthase CIT1	Saccharomyces cerevisiae S288C	34-39	
10587442-4	1999	A cytosolically localized form of Cit1p was also incompetent for restoration of growth of a Deltacit1 strain on acetate, suggesting that mitochondrial localization of Cit1p is essential for its function in the TCA cycle.	Tricarboxylic Acids	210-213	citrate (Si)-synthase CIT1	Saccharomyces cerevisiae S288C	167-172