PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22773836-0	2012	Angiotensin-II and MARCKS: a hydrogen peroxide- and RAC1-dependent signaling pathway in vascular endothelium.	Hydrogen Peroxide	29-46	myristoylated alanine rich protein kinase C substrate	Homo sapiens	19-25	
22773836-6	2012	In endothelial cells, angiotensin-II-promoted MARCKS phosphorylation is abrogated by PEG-catalase, implicating endogenous H(2)O(2) in the angiotensin-II response.	Hydrogen Peroxide	122-130	myristoylated alanine rich protein kinase C substrate	Homo sapiens	46-52	
22773836-12	2012	These studies establish a critical role for H(2)O(2) in angiotensin-II signaling to the endothelial cytoskeleton in a novel pathway that is critically dependent on MARCKS, Rac1, and c-Abl.	Hydrogen Peroxide	44-52	myristoylated alanine rich protein kinase C substrate	Homo sapiens	164-170	
7889145-7	1995	To assess the effects of H2O2 treatment on PKC activation, we measured phosphorylation of an endogenous PKC substrate, the MARCKS (myristoylated alanine-rich C kinase substrate) protein.	Hydrogen Peroxide	25-29	myristoylated alanine rich protein kinase C substrate	Homo sapiens	131-176	
7889145-8	1995	Treatment of cells with 0.2-1.0 mM H2O2 resulted in a rapid increase in MARCKS phosphorylation.	Hydrogen Peroxide	35-39	myristoylated alanine rich protein kinase C substrate	Homo sapiens	72-78	
7889145-11	1995	The H2O2-induced MARCKS phosphorylation was inhibited by the addition of the kinase inhibitors H-7 and staurosporine.	Hydrogen Peroxide	4-8	myristoylated alanine rich protein kinase C substrate	Homo sapiens	17-23	
7889145-12	1995	Furthermore, specific down-regulation of PKC by phorbol ester also inhibited H2O2-induced MARCKS phosphorylation.	Hydrogen Peroxide	77-81	myristoylated alanine rich protein kinase C substrate	Homo sapiens	90-96