PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28849090-9 2017 H2O2 markedly upregulated the expression levels of KLF4 and KLF5, and downregulated the expression levels of miR-506 and miR-124 in the HCMs. Hydrogen Peroxide 0-4 microRNA 506 Homo sapiens 109-116 28849090-11 2017 The overexpression of miR-506 and miR-124 inhibited the H2O2-induced upregulation of KLF4 and KLF5 in the HCMs. Hydrogen Peroxide 56-60 microRNA 506 Homo sapiens 22-29 28849090-12 2017 The overexpression of miR-506 and miR-214 reversed the H2O2-induced apoptosis and increase of ROS in the HCMs. Hydrogen Peroxide 55-59 microRNA 506 Homo sapiens 22-29 28849090-13 2017 In conclusion, the overexpression of miR-506 and miR-214 were confirmed to have a protective effect against H2O2-induced HCM injury by suppressing the expression of KLF4 and KLF5. Hydrogen Peroxide 108-112 microRNA 506 Homo sapiens 37-44