PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22400069-8 2012 In the present study, we determined whether Foxo1 regulates Na(V)1.5 expression at the transcriptional level and also defined the role of Foxo1 in hydrogen peroxide (H(2)O(2))-mediated Na(V)1.5 suppression in HL-1 cardiomyocytes using chromatin immunoprecipitation (ChIP), constitutively nuclear Foxo1 expression, and RNAi Foxo1 knockdown as well as whole cell voltage-clamp recordings. Hydrogen Peroxide 147-164 immunoglobulin lambda variable 2-18 Homo sapiens 185-193