PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33185367-7	2021	Tacrolimus/m-TOR inhibitors were reduced by 50% and all antimetabolites were discontinued.	Tacrolimus	0-10	RAR related orphan receptor C	Homo sapiens	13-16	
33195437-5	2020	Two small molecules FK506 and rapamycin bind to FKBP12 immunophilin and the resulting complexes (FK506-FKBP12 and rapamycin-FKBP12) target calcineurin and TOR, respectively in both humans and fungi.	Tacrolimus	20-25	RAR related orphan receptor C	Homo sapiens	155-158	
33195437-5	2020	Two small molecules FK506 and rapamycin bind to FKBP12 immunophilin and the resulting complexes (FK506-FKBP12 and rapamycin-FKBP12) target calcineurin and TOR, respectively in both humans and fungi.	Tacrolimus	97-102	RAR related orphan receptor C	Homo sapiens	155-158	
33195437-8	2020	The current review highlights FK506/rapamycin-FKBP12 interactions with calcineurin/TOR kinase in human and fungi, and development of non-immunosuppressive analogs of FK506, rapamycin, and novel small molecules in inhibition of fungal calcineurin and TOR kinase.	Tacrolimus	30-35	RAR related orphan receptor C	Homo sapiens	83-86	
33195437-8	2020	The current review highlights FK506/rapamycin-FKBP12 interactions with calcineurin/TOR kinase in human and fungi, and development of non-immunosuppressive analogs of FK506, rapamycin, and novel small molecules in inhibition of fungal calcineurin and TOR kinase.	Tacrolimus	30-35	RAR related orphan receptor C	Homo sapiens	250-253