PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14559856-0 2003 FK506 potentiates NGF-induced neurite outgrowth via the Ras/Raf/MAP kinase pathway. Tacrolimus 0-5 zinc fingers and homeoboxes 2 Homo sapiens 60-63 14559856-4 2003 Inhibitors of Ras (lovastatin), Raf (GW5074), or MAP kinase (PD98059 and U0126) blocked FK506 activity, as did inhibitors of phospholipase C (U73122) and phosphatidylinositol 3" kinase (LY294002). Tacrolimus 88-93 zinc fingers and homeoboxes 2 Homo sapiens 32-35 14559856-6 2003 These data suggest that FK506 potentiates neurite outgrowth through the Ras/Raf/MAP kinase signaling pathway downstream of phospholipase C and phosphatidylinositol 3" kinase. Tacrolimus 24-29 zinc fingers and homeoboxes 2 Homo sapiens 76-79 8774885-4 1996 Oligomerization of recombinant FKBP-Raf in situ, induced by the addition of the dimeric FK506 derivative FK1012A, activated Raf kinase activity at least half as well as epidermal growth factor (EGF). Tacrolimus 88-93 zinc fingers and homeoboxes 2 Homo sapiens 36-39 8774885-4 1996 Oligomerization of recombinant FKBP-Raf in situ, induced by the addition of the dimeric FK506 derivative FK1012A, activated Raf kinase activity at least half as well as epidermal growth factor (EGF). Tacrolimus 88-93 zinc fingers and homeoboxes 2 Homo sapiens 124-127