PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30718414-10	2019	In vivo, tacrolimus increases levels of KLHL3S433-P, resulting in increased levels of WNK4, phosphorylated SPAK, and NCC.	Tacrolimus	9-19	WNK lysine deficient protein kinase 4	Homo sapiens	86-90	
30718414-11	2019	Moreover, tacrolimus attenuates KLHL3-mediated WNK4 ubiquitylation and degradation, while this effect is absent in KLHL3 with S433A substitution.	Tacrolimus	10-20	WNK lysine deficient protein kinase 4	Homo sapiens	47-51