PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12381413-9	2002	Stills others such as the immunosuppressants cyclosporine A and FK506/tacrolimus or erythropoietin have inconsistent effects on eNOS.	Tacrolimus	64-69	nitric oxide synthase 3	Homo sapiens	128-132	
12381413-9	2002	Stills others such as the immunosuppressants cyclosporine A and FK506/tacrolimus or erythropoietin have inconsistent effects on eNOS.	Tacrolimus	70-80	nitric oxide synthase 3	Homo sapiens	128-132	
12352326-9	2002	Endothelial NOS mRNA was increased in cyclosporine-and tacrolimus-treated patients in comparison with controls (0.92 +/- 0.09, 0.96 +/- 0.04, and 0.37 +/- 0.05 respectively; p < 0.001), whereas no difference was found between patients and controls in HO-1 mRNA.	Tacrolimus	55-65	nitric oxide synthase 3	Homo sapiens	0-15	
21383022-0	2011	Protein kinase CbetaII-mediated phosphorylation of endothelial nitric oxide synthase threonine 495 mediates the endothelial dysfunction induced by FK506 (tacrolimus).	Tacrolimus	147-152	nitric oxide synthase 3	Homo sapiens	51-84	
21383022-0	2011	Protein kinase CbetaII-mediated phosphorylation of endothelial nitric oxide synthase threonine 495 mediates the endothelial dysfunction induced by FK506 (tacrolimus).	Tacrolimus	154-164	nitric oxide synthase 3	Homo sapiens	51-84	
21383022-2	2011	We have previously shown that FK506 activates Ca(2+)/diacylglycerol-dependent conventional protein kinase C (cPKC), which phosphorylates endothelial nitric oxide synthase (eNOS) at one of its inhibitory sites, Thr495.	Tacrolimus	30-35	nitric oxide synthase 3	Homo sapiens	137-170