PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3660410-10 1987 Dantrolene and mepacrine antagonized the synergism between halothane and phospholipase A2 most likely by reducing the lytic action of halothane in the presence of arachidonic acid. Halothane 134-143 phospholipase A2 group IB Homo sapiens 73-89 3660410-6 1987 Halothane addition caused 100% hydrolysis of all diacylphosphoglycerides by phospholipase A2, suggesting a mutual potentiation. Halothane 0-9 phospholipase A2 group IB Homo sapiens 76-92 3660410-7 1987 The major products of phospholipase A2 activity, arachidonic acid and lysophosphatidylcholine, when exogenously added, also greatly increased hemolysis induced by halothane, with arachidonic acid most closely resembling the synergism observed with phospholipase A2. Halothane 163-172 phospholipase A2 group IB Homo sapiens 22-38 3608052-3 1987 Halothane caused haemolysis of erythrocytes in an isoosmolar solution, being more potent at 42 degrees C than at 32 degrees C. Haemolysis produced by an hypoosmolar medium or halothane was potentiated by exogenously added phospholipase A2. Halothane 0-9 phospholipase A2 group IB Homo sapiens 222-238 3608052-3 1987 Halothane caused haemolysis of erythrocytes in an isoosmolar solution, being more potent at 42 degrees C than at 32 degrees C. Haemolysis produced by an hypoosmolar medium or halothane was potentiated by exogenously added phospholipase A2. Halothane 175-184 phospholipase A2 group IB Homo sapiens 222-238 3790395-6 1986 The three PLA2 inhibitors antagonized halothane-induced contractures of muscle from MH susceptible patients as well as induction of contractures by suxamethonium and halothane. Halothane 38-47 phospholipase A2 group IB Homo sapiens 10-14 3790395-6 1986 The three PLA2 inhibitors antagonized halothane-induced contractures of muscle from MH susceptible patients as well as induction of contractures by suxamethonium and halothane. Halothane 166-175 phospholipase A2 group IB Homo sapiens 10-14 3790395-7 1986 Pre-exposing preparations that were previously unresponsive to halothane to bee venom PLA2 caused the muscle strips to respond with contractures upon subsequent challenge with halothane, but not with suxamethonium. Halothane 176-185 phospholipase A2 group IB Homo sapiens 86-90