PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12325046-5 2002 SPECT studies 4, 10, and 31 days after MDMA treatment revealed decreases in [123I]beta-CIT binding ratios in the SERT-rich brain region studied (hypothalamic/midbrain region), with SERT density reduced by 39% in this brain region 31 days after treatment. 2beta-carbomethoxy-3beta-(4-iodophenyl)tropane 82-90 solute carrier family 6 member 4 Rattus norvegicus 113-117 23115651-3 2012 METHODS: 5-HT transporter (SERT) densities in the frontal cortex and midbrain were assessed with [(123)I]beta-CIT single photon emission computed tomography in 33 users of ecstasy. 2beta-carbomethoxy-3beta-(4-iodophenyl)tropane 105-113 solute carrier family 6 member 4 Rattus norvegicus 9-25 23115651-3 2012 METHODS: 5-HT transporter (SERT) densities in the frontal cortex and midbrain were assessed with [(123)I]beta-CIT single photon emission computed tomography in 33 users of ecstasy. 2beta-carbomethoxy-3beta-(4-iodophenyl)tropane 105-113 solute carrier family 6 member 4 Rattus norvegicus 27-31 19453722-7 2009 The interaction between CBZ and 125I beta-CIT binding to SERT and DAT was investigated using in vitro autoradiography. 2beta-carbomethoxy-3beta-(4-iodophenyl)tropane 37-45 solute carrier family 6 member 4 Rattus norvegicus 57-61 12325046-7 2002 In addition, ex vivo [123I]beta-CIT binding studies in rats 1 week after treatment with neurotoxic doses of MDMA (20 mg/kg s.c. twice daily for 4 consecutive days) revealed significant reductions in [123I]beta-CIT binding in SERT-rich regions (including the hypothalamus) when compared to saline-treated rats. 2beta-carbomethoxy-3beta-(4-iodophenyl)tropane 27-35 solute carrier family 6 member 4 Rattus norvegicus 225-229 12325046-8 2002 The combined results of these studies indicate that SPECT imaging of SERT with [123I]beta-CIT can detect changes in SERT density secondary to MDMA-induced neurotoxicity in the hypothalamic/midbrain region, and possibly other brain regions. 2beta-carbomethoxy-3beta-(4-iodophenyl)tropane 85-93 solute carrier family 6 member 4 Rattus norvegicus 69-73 12325046-8 2002 The combined results of these studies indicate that SPECT imaging of SERT with [123I]beta-CIT can detect changes in SERT density secondary to MDMA-induced neurotoxicity in the hypothalamic/midbrain region, and possibly other brain regions. 2beta-carbomethoxy-3beta-(4-iodophenyl)tropane 85-93 solute carrier family 6 member 4 Rattus norvegicus 116-120 11062247-2 2001 Specific binding of RTI-233 to the rat serotonin transporter, purified from Sf-9 insect cells, was demonstrated by the competitive inhibition of fluorescence using excess serotonin, citalopram, or RTI-55 (2beta-carbomethoxy-3beta-(4-iodophenyl)tropane). 2beta-carbomethoxy-3beta-(4-iodophenyl)tropane 197-203 solute carrier family 6 member 4 Rattus norvegicus 39-60 11062247-2 2001 Specific binding of RTI-233 to the rat serotonin transporter, purified from Sf-9 insect cells, was demonstrated by the competitive inhibition of fluorescence using excess serotonin, citalopram, or RTI-55 (2beta-carbomethoxy-3beta-(4-iodophenyl)tropane). 2beta-carbomethoxy-3beta-(4-iodophenyl)tropane 205-251 solute carrier family 6 member 4 Rattus norvegicus 39-60 9843724-0 1998 Relationship between [125I]RTI-55-labeled cocaine binding sites and the serotonin transporter in rat placenta. 2beta-carbomethoxy-3beta-(4-iodophenyl)tropane 27-33 solute carrier family 6 member 4 Rattus norvegicus 72-93 1385663-1 1992 [123I]RTI-55, an iodinated derivative of the cocaine analog 3 beta-phenyltropane-2 beta-carboxylic acid methyl ester, was evaluated as an agent for in vivo labeling of the serotonin transporter. 2beta-carbomethoxy-3beta-(4-iodophenyl)tropane 6-12 solute carrier family 6 member 4 Rattus norvegicus 172-193