PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24450852-7	2014	We delineate the intracellular signaling that promotes cytoprotection: Cicaprost acts via the IP-R/protein kinase A (PKA)/cyclic adenosine monophosphate (cAMP) response element binding (CREB) protein pathway.	cicaprost	71-80	cAMP responsive element binding protein 1	Homo sapiens	186-190	
24450852-10	2014	INNOVATION: The prostacyclin analogue cicaprost induces Nox4 via IP receptor-cAMP/PKA/CREB pathway.	cicaprost	38-47	cAMP responsive element binding protein 1	Homo sapiens	86-90	
12869629-6	2003	Complementary studies showed that occupancy of the cAMP response element (CRE) is required for efficient activation of the cyclin A promoter in aortic smooth muscle cells, that the CRE is primarily occupied by the CRE-binding protein (CREB) and phospho-CREB, and that cicaprost blocks the binding of CREB and phospho-CREB to the cyclin A promoter CRE.	cicaprost	268-277	cAMP responsive element binding protein 1	Homo sapiens	214-233	
12869629-6	2003	Complementary studies showed that occupancy of the cAMP response element (CRE) is required for efficient activation of the cyclin A promoter in aortic smooth muscle cells, that the CRE is primarily occupied by the CRE-binding protein (CREB) and phospho-CREB, and that cicaprost blocks the binding of CREB and phospho-CREB to the cyclin A promoter CRE.	cicaprost	268-277	cAMP responsive element binding protein 1	Homo sapiens	235-239