PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21285081-10 2011 Restoration of consciousness by physostigmine was associated with rCBF increases in these same structures, with the strongest effect in the thalamus. Physostigmine 32-45 CCAAT/enhancer binding protein zeta Rattus norvegicus 66-70 21914840-7 2011 RESULTS: Physostigmine significantly decreased hippocampal rCBF in control subjects (P < .0005) and veterans with syndrome 1 (P < .05) but significantly increased hippocampal rCBF in veterans with syndrome 2 (P < .005) and veterans with syndrome 3 (P < .002). Physostigmine 9-22 CCAAT/enhancer binding protein zeta Rattus norvegicus 59-63 21914840-7 2011 RESULTS: Physostigmine significantly decreased hippocampal rCBF in control subjects (P < .0005) and veterans with syndrome 1 (P < .05) but significantly increased hippocampal rCBF in veterans with syndrome 2 (P < .005) and veterans with syndrome 3 (P < .002). Physostigmine 9-22 CCAAT/enhancer binding protein zeta Rattus norvegicus 181-185 10718513-1 2000 Previously, we have shown that physostigmine, an acetylcholinesterase inhibitor, improved performance on a working memory for faces task, as reflected by reduced reaction time (RT), and reduced task-specific regional cerebral blood flow (rCBF) in right prefrontal cortex and, further, that these reductions in RT and right frontal rCBF were significantly correlated. Physostigmine 31-44 CCAAT/enhancer binding protein zeta Rattus norvegicus 238-242 18284346-11 2008 In all of these prefrontal regions, physostigmine administration significantly reduced rCBF during task, particularly at longer task delays, so that no correlation between task delay and rCBF was observed. Physostigmine 36-49 CCAAT/enhancer binding protein zeta Rattus norvegicus 87-91 18284346-12 2008 In the ventral visual cortex, physostigmine increased rCBF at longer task delays in medial regions, and decreased rCBF over delay conditions in lateral cortical areas. Physostigmine 30-43 CCAAT/enhancer binding protein zeta Rattus norvegicus 54-58 18284346-12 2008 In the ventral visual cortex, physostigmine increased rCBF at longer task delays in medial regions, and decreased rCBF over delay conditions in lateral cortical areas. Physostigmine 30-43 CCAAT/enhancer binding protein zeta Rattus norvegicus 114-118 16263845-8 2005 The right prefrontal regions that were selectively recruited in each age group during the placebo condition showed significantly lower rCBF during physostigmine administration. Physostigmine 147-160 CCAAT/enhancer binding protein zeta Rattus norvegicus 135-139 10718513-1 2000 Previously, we have shown that physostigmine, an acetylcholinesterase inhibitor, improved performance on a working memory for faces task, as reflected by reduced reaction time (RT), and reduced task-specific regional cerebral blood flow (rCBF) in right prefrontal cortex and, further, that these reductions in RT and right frontal rCBF were significantly correlated. Physostigmine 31-44 CCAAT/enhancer binding protein zeta Rattus norvegicus 331-335 10718513-2 2000 Here we investigated the relation between the effects of physostigmine on task performance and task-specific functional brain response throughout the cortex by examining correlations between physostigmine-related changes in rCBF in all brain areas and changes in RT. Physostigmine 191-204 CCAAT/enhancer binding protein zeta Rattus norvegicus 224-228 10718513-3 2000 In subjects who received an infusion of physostigmine, reduced RT correlated (p<0.001) positively with reduced rCBF in right frontal cortex, left temporal cortex, anterior cingulate, and left hippocampus; and correlated with increased rCBF in medial occipital visual cortex. Physostigmine 40-53 CCAAT/enhancer binding protein zeta Rattus norvegicus 114-118 10718513-3 2000 In subjects who received an infusion of physostigmine, reduced RT correlated (p<0.001) positively with reduced rCBF in right frontal cortex, left temporal cortex, anterior cingulate, and left hippocampus; and correlated with increased rCBF in medial occipital visual cortex. Physostigmine 40-53 CCAAT/enhancer binding protein zeta Rattus norvegicus 238-242 9070622-1 1997 The effects of scopolamine, a muscarinic cholinergic receptor antagonist and physostigmine, a cholinesterase inhibitor, on the regional cerebral blood flow (rCBF) response to vibrotactile stimulation of the forepaw were studied in the brain of unanesthetized monkeys using 15O-labeled water and high resolution positron emission tomography. Physostigmine 77-90 CCAAT/enhancer binding protein zeta Rattus norvegicus 157-161 9190877-4 1997 The rCBF response abolished by pretreatment with scopolamine was recovered by administration of physostigmine (1 or 10 microg/kg), E2020 (10 or 100 microg/kg) or tacrine (100 or 1000 microg/kg), in a dose-dependent manner. Physostigmine 96-109 CCAAT/enhancer binding protein zeta Rattus norvegicus 4-8 9070622-4 1997 The rCBF response abolished by scopolamine (50 microg/kg) was recovered by administration of physostigmine (10 microg/kg). Physostigmine 93-106 CCAAT/enhancer binding protein zeta Rattus norvegicus 4-8 2054572-2 1991 Central cholinergic stimulation with physostigmine produced a focal increase in rCBF in the posterior parietotemporal region in the patients with AD but not in controls. Physostigmine 37-50 CCAAT/enhancer binding protein zeta Rattus norvegicus 80-84 2036533-1 1991 The effects of physostigmine on patterns of rCBF in patients with pre-senile Alzheimer"s disease were studied using 99mTc-labelled HMPAO SPECT. Physostigmine 15-28 CCAAT/enhancer binding protein zeta Rattus norvegicus 44-48 1856884-6 1991 Physostigmine intravenous infusion (3.3 micrograms.kg-1.min-1) enhanced rCBF in frontal, parietal, occipital, and temporal cortex. Physostigmine 0-13 CCAAT/enhancer binding protein zeta Rattus norvegicus 72-76 1972432-2 1990 Central cholinergic stimulation with physostigmine produced a focal increase in rCBF in the posterior parietotemporal region in the patients with AD but not in controls. Physostigmine 37-50 CCAAT/enhancer binding protein zeta Rattus norvegicus 80-84