PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11405996-20 2001 The best dose physostigmine (mean 25mg/day) was associated with a 1.75 point improvement on ADAS-Cog score (mean difference -1.75, 95% confidence interval -2.90, -0.60 on an intention-to-treat basis) and a 0.26 point improvement on the CGIC score (treated as a continuous scale) (mean difference -0.26, 95% confidence interval 0.06, 0.46 on an intention-to-treat basis) compared with placebo at 6 weeks. Physostigmine 14-27 alkylglycerone phosphate synthase Homo sapiens 92-96 11405996-22 2001 The best dose physostigmine (mean 27mg/day) was associated with a 2.0 point improvement on ADAS-Cog score (mean difference -2.02, 95% confidence interval -3.59, -0.45 on an intention to treat basis) compared with placebo at 12 weeks. Physostigmine 14-27 alkylglycerone phosphate synthase Homo sapiens 91-95 10214735-8 1999 RESULTS: In an intent-to-treat population, the last observation carried forward analysis revealed a 2.9-point ADAS-Cog (p = 0.002) difference between physostigmine and placebo-treated patients for both dosages, and a 0.26 to 0.31-point difference on the CIBIC+ (p = 0.048). Physostigmine 150-163 alkylglycerone phosphate synthase Homo sapiens 110-114