PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8625423-0	1996	Aromatic amino-acid biosynthesis in Candida albicans: identification of the ARO4 gene encoding a second DAHP synthase.	Amino Acids, Aromatic	0-19	3-deoxy-7-phosphoheptulonate synthase ARO4	Saccharomyces cerevisiae S288C	76-80	
21385868-5	2011	The results suggest that in the absence of Grx2p, the metabolic flow toward nucleotide and aromatic amino acid biosynthesis is slowed down by redox modification of the key enzymes Rpe1p (D-ribulose-5-phosphate 3-epimerase), Tkl1p (transketolase) and Aro4p (3-deoxy-D-arabino-heptulosonate-7-phosphate synthase).	Amino Acids, Aromatic	91-110	3-deoxy-7-phosphoheptulonate synthase ARO4	Saccharomyces cerevisiae S288C	250-255	
29744630-9	2018	Genome sequencing of these newly developed strains revealed mutations in two genes of the biosynthetic pathway of aromatic amino acids, ARO4 and TYR1, which were demonstrated to be responsible for the 2-PE overproduction phenotype.	Amino Acids, Aromatic	114-134	3-deoxy-7-phosphoheptulonate synthase ARO4	Saccharomyces cerevisiae S288C	136-140	
23216753-8	2012	Synthesis of aromatic amino acids was deregulated by alleviating feedback inhibition of 3-deoxy-d-arabinose-heptulosonate-7-phosphate synthase (Aro3, Aro4) and byproduct formation was reduced by eliminating phenylpyruvate decarboxylase (Aro10, Pdc5, Pdc6).	Amino Acids, Aromatic	13-33	3-deoxy-7-phosphoheptulonate synthase ARO4	Saccharomyces cerevisiae S288C	150-154	
18372204-7	2008	However when they were combined with the Tyr-insensitive ARO4 allele in combination with the Tyr-insensitive ARO4 allele, extracellular concentrations of aromatic compounds were increased by over 200-fold relative to the reference strain, corresponding to a 4.5-fold increase of the flux through the aromatic amino acid biosynthesis pathway.	Amino Acids, Aromatic	300-319	3-deoxy-7-phosphoheptulonate synthase ARO4	Saccharomyces cerevisiae S288C	57-61