PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21319191-4	2011	Gallbladder bile acid composition changed from predominantly cholic acid (57%) in wild-type to chenodeoxycholic acid (54%) in Cyp7a1-tg mice.	Chenodeoxycholic Acid	95-116	cytochrome P450, family 7, subfamily a, polypeptide 1	Mus musculus	126-132	
12509506-5	2003	WhenCyp27a1(-/-) mice are fed a diet containing either cholic acid or chenodeoxycholic acid, expression of CYP7A1, which catalyzes the rate-limiting step in bile acid biosynthesis, is strongly suppressed.	Chenodeoxycholic Acid	70-91	cytochrome P450, family 7, subfamily a, polypeptide 1	Mus musculus	107-113	
33193099-0	2020	Downregulation of Cyp7a1 by Cholic Acid and Chenodeoxycholic Acid in Cyp27a1/ApoE Double Knockout Mice: Differential Cardiovascular Outcome.	Chenodeoxycholic Acid	44-65	cytochrome P450, family 7, subfamily a, polypeptide 1	Mus musculus	18-24	
10823815-4	2000	Studies using cultured THP-1 monocyte/macrophages showed that the hydrophobic bile acid chenodeoxycholate, a well established potent repressor of CYP7A1, induced the expression of mRNAs encoding interleukin 1 (IL-1) and tumor necrosis factor alpha (TNFalpha).	Chenodeoxycholic Acid	88-105	cytochrome P450, family 7, subfamily a, polypeptide 1	Mus musculus	146-152	
35614477-8	2022	Serum levels of chenodeoxycholic acid and deoxycholic acid tended to be decreased in the HNF4alpha HET mice but dramatically increased in the HNF4alpha KO mice, which was associated with marked down-regulation of cytochrome P450 7a1, the rate-limiting enzyme for bile acid synthesis.	Chenodeoxycholic Acid	16-37	cytochrome P450, family 7, subfamily a, polypeptide 1	Mus musculus	213-232	
33193099-6	2020	Hepatic Cyp7a1 and Cyp3a11 expression were reduced by 60% after feeding with both WD-CA and WD-CDCA.	Chenodeoxycholic Acid	95-99	cytochrome P450, family 7, subfamily a, polypeptide 1	Mus musculus	8-14	
25582706-7	2015	Cyp7a1, the rate-limiting enzyme in BA synthesis, was decreased more by CA and DCA than CDCA and LCA.	Chenodeoxycholic Acid	88-92	cytochrome P450, family 7, subfamily a, polypeptide 1	Mus musculus	0-6	
25447797-0	2015	Impact of physiological levels of chenodeoxycholic acid supplementation on intestinal and hepatic bile acid and cholesterol metabolism in Cyp7a1-deficient mice.	Chenodeoxycholic Acid	34-55	cytochrome P450, family 7, subfamily a, polypeptide 1	Mus musculus	138-144	
25447797-3	2015	Here we demonstrate that in Cyp7a1(-/-) mice fed chenodeoxycholic acid (CDCA) at a level of 0.06% (w/w), the BAP was restored to normal size and became substantially enriched with muricholic acid (MCA) (>70%), leaving the combined contribution of CA and CDCA to be <15%.	Chenodeoxycholic Acid	49-70	cytochrome P450, family 7, subfamily a, polypeptide 1	Mus musculus	28-34	
25447797-3	2015	Here we demonstrate that in Cyp7a1(-/-) mice fed chenodeoxycholic acid (CDCA) at a level of 0.06% (w/w), the BAP was restored to normal size and became substantially enriched with muricholic acid (MCA) (>70%), leaving the combined contribution of CA and CDCA to be <15%.	Chenodeoxycholic Acid	72-76	cytochrome P450, family 7, subfamily a, polypeptide 1	Mus musculus	28-34	
25447797-3	2015	Here we demonstrate that in Cyp7a1(-/-) mice fed chenodeoxycholic acid (CDCA) at a level of 0.06% (w/w), the BAP was restored to normal size and became substantially enriched with muricholic acid (MCA) (>70%), leaving the combined contribution of CA and CDCA to be <15%.	Chenodeoxycholic Acid	257-261	cytochrome P450, family 7, subfamily a, polypeptide 1	Mus musculus	28-34