PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12445472-4	2002	We demonstrate that vWF and tPA which are stored in different granules within endothelial cells are released with different kinetics following endothelial stimulation with histamine or the Ca(2+) ionophore A23187.	Histamine	172-181	plasminogen activator, tissue type	Homo sapiens	28-31	
11078636-5	2000	The effects of ECGF, histamine, and LPS on the presence of tPA and on enhancing the levels of mRNA reached maximum activity at 4 h and declined to levels below that of controls by 8 h. However, phorbol-treated cells exhibited reduced levels of tPA mRNA at 4 h, but was significantly increased by 8 h. A large-scale increase in PAI-1 mRNA steady-state levels was also stimulated by the agonists used in these studies.	Histamine	21-30	plasminogen activator, tissue type	Homo sapiens	59-62	
11986218-8	2002	Incubation with histamine, forskolin, and epinephrine induced the rapid, coordinate release of both t-PA and VWF, consistent with a single storage compartment.	Histamine	16-25	plasminogen activator, tissue type	Homo sapiens	100-104	
7510984-4	1994	(3) The late-phase histamine-containing cells in late-phase BAL fluids have the functional characteristics of basophils in their secretory responses to anti-IgE, the f-met peptide, and phorbol ester TPA.	Histamine	19-28	plasminogen activator, tissue type	Homo sapiens	199-202	
7578901-1	1995	The acute simultaneous release of tissue plasminogen activator (t-PA) and von Willebrand factor (vWF) from endothelial cells in response to a variety of agonists including thrombin, DDAVP, histamine and adrenalin has been described.	Histamine	189-198	plasminogen activator, tissue type	Homo sapiens	34-68	
8029817-7	1994	The release of t-PA and PAI-1 from vascular endothelial cells is regulated by physiological factors including thrombin (3,7), histamine (8), vasoconstrictor peptide endothelins (9,10) and cytokines (11).	Histamine	126-135	plasminogen activator, tissue type	Homo sapiens	15-19	
1700888-12	1990	In the presence of 10 ng/ml TPA, however, seven of 10 patients released histamine at anti-IgE challenge.	Histamine	72-81	plasminogen activator, tissue type	Homo sapiens	28-31	
2545266-3	1989	These agents also significantly reduced or abolished the previously reported stimulatory effects of thrombin and histamine on t-PA secretion, and, with the exception of MIX, significantly reduced the previously reported stimulatory effect of thrombin on PAI-1 secretion.	Histamine	113-122	plasminogen activator, tissue type	Homo sapiens	126-130	
3098881-8	1987	Endotoxin stimulation resulted in a specific secretion of PA-I activity but not of t-PA Ag, whereas histamine stimulation at concentrations of 0.1 to 1 mumol/L caused a specific secretion of t-PA Ag but not of PA-I.	Histamine	100-109	plasminogen activator, tissue type	Homo sapiens	191-195	
18647223-9	2008	Both forskolin and histamine induced regulated release of t-PA.	Histamine	19-28	plasminogen activator, tissue type	Homo sapiens	58-62