PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9535029-0 1998 Regulation of H1-receptor coupling and H1-receptor mRNA by histamine in bovine tracheal smooth muscle. Histamine 59-68 histamine H1 receptor Bos taurus 14-25 16627364-7 2006 Two known mast cell-derived mediators, histamine and thromboxane A2, via stable mimetic U46619 also altered lymphatic pumping in a similar manner, but only pretreatment with the histamine H1 receptor antagonist pyrilamine (1 microM) could reduce the beta-lactoglobulin-induced response. Histamine 39-48 histamine H1 receptor Bos taurus 178-199 9535029-0 1998 Regulation of H1-receptor coupling and H1-receptor mRNA by histamine in bovine tracheal smooth muscle. Histamine 59-68 histamine H1 receptor Bos taurus 39-50 9535029-9 1998 Furthermore, histamine pre-incubation in calcium free medium still induced a functional uncoupling of H1R. Histamine 13-22 histamine H1 receptor Bos taurus 102-105 9535029-15 1998 These results suggest that histamine induces desensitization of the H1R at the level of the receptor protein, which involves a mechanism independent of PKC, PKA, PKG and calcium influx, suggesting the involvement of a receptor-specific kinase. Histamine 27-36 histamine H1 receptor Bos taurus 68-71 9196269-5 1997 However, when the response to histamine was evaluated in the presence of mepyramine and histamine H1 and H3 receptors were blocked, Schild analysis yielded a line with a slope of 1.10 and a pA2 value of 8.91, indicating simple competitive antagonism of mepyramine at histamine H1 receptor sites. Histamine 30-39 histamine H1 receptor Bos taurus 267-288 9180359-3 1997 Histamine (10(-8)-10(-5) M)-induced catecholamine secretion was markedly potentiated by addition of ouabain (10(-5) M) and was inhibited by a histamine-H1 receptor antagonist or incubation in a Ca2+-free medium. Histamine 0-9 histamine H1 receptor Bos taurus 142-163