PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33038289-5	2021	Both studies confirmed longer half-lives for active metabolites and lower peak-to-trough fluctuations for the sum of the metabolites (total [alpha+beta]-HTBZ) following deutetrabenazine compared with tetrabenazine (3- to 4-fold and 11-fold, respectively) in steady-state conditions.	Tetrabenazine	172-185	amyloid beta precursor protein	Homo sapiens	141-151	
33038289-6	2021	Deutetrabenazine doses estimated to provide total (alpha+beta)-HTBZ exposure comparable to tetrabenazine 25 mg were 11.4-13.2 mg. Food had no effect on exposure to total (alpha+beta)-HTBZ, as measured by AUC.	Tetrabenazine	3-16	amyloid beta precursor protein	Homo sapiens	51-61	
33038289-7	2021	Although the total (alpha+beta)-HTBZ Cmax of deutetrabenazine was increased by  50% in the presence of food, it remained lower than that of tetrabenazine.	Tetrabenazine	48-61	amyloid beta precursor protein	Homo sapiens	20-30