PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18582477-3 2008 Primer extension on an 88 bp triplex-forming polypurine.polypyrimidine (Pu.Py) tract from the PKD1 gene demonstrated that RecQ, but not RecG, facilitated primer extension by T7 DNA polymerase. polypyrimidine 56-70 polycystin 1, transient receptor potential channel interacting Homo sapiens 94-98 30185468-2 2018 Unlike PKD1 genes in the mouse and most other mammals, human PKD1 is unusual in that it contains two long polypyrimidine tracts in introns 21 and 22 (2.5 kbp and 602 bp, respectively; 97% cytosine and thymine). polypyrimidine 106-120 polycystin 1, transient receptor potential channel interacting Homo sapiens 61-65 30185468-7 2018 CONCLUSIONS: The presence of polypyrimidine tracts decreases levels of full-length PKD1 mRNA from normal alleles. polypyrimidine 29-43 polycystin 1, transient receptor potential channel interacting Homo sapiens 83-87 11336403-0 2001 Amplification of a 13.5-kb region of the PKD1 gene containing the 2.5-kb polypyrimidine tract in intron 21 facilitates mutation detection in this gene. polypyrimidine 73-87 polycystin 1, transient receptor potential channel interacting Homo sapiens 41-45 18060739-2 2008 PKD1 has an unusual genomic structure, including a 2.5-kb polypyrimidine sequence in intron 21, which has been postulated to lead to a high rate of spontaneous genomic mutation events. polypyrimidine 58-72 polycystin 1, transient receptor potential channel interacting Homo sapiens 0-4 14990751-2 2004 The polypurine.polypyrimidine (Pu.Py) tract of PKD1 intron 21 may play a role in promoting somatic mutations. polypyrimidine 15-29 polycystin 1, transient receptor potential channel interacting Homo sapiens 47-51 11336403-2 2001 Long-range PCR has been used previously to overcome this limitation, but due to a 2.5-kb polypyrimidine tract in intron 21, the screening capacity of the PKD1 gene using this technique was hindered. polypyrimidine 89-103 polycystin 1, transient receptor potential channel interacting Homo sapiens 154-158 10373576-11 1999 In summary, these experiments demonstrate that a 2500 bp polypurine.polypyrimidine tract within the PKD1 gene is capable of forming multiple non-B-DNA structures. polypyrimidine 68-82 polycystin 1, transient receptor potential channel interacting Homo sapiens 100-104 9922404-0 1999 Murine Pkd1 introns 21 and 22 lack the extreme polypyrimidine bias present in human PKD1. polypyrimidine 47-61 polycystin 1, transient receptor potential channel interacting Homo sapiens 7-11 9922404-0 1999 Murine Pkd1 introns 21 and 22 lack the extreme polypyrimidine bias present in human PKD1. polypyrimidine 47-61 polycystin 1, transient receptor potential channel interacting Homo sapiens 84-88 9689215-0 1996 A 2.5 kb polypyrimidine tract in the PKD1 gene contains at least 23 H-DNA-forming sequences. polypyrimidine 9-23 polycystin 1, transient receptor potential channel interacting Homo sapiens 37-41