PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16785233-0	2006	Arsenic induces NAD(P)H-quinone oxidoreductase I by disrupting the Nrf2 x Keap1 x Cul3 complex and recruiting Nrf2 x Maf to the antioxidant response element enhancer.	Arsenic	0-7	MAF bZIP transcription factor	Homo sapiens	117-120	
16785233-7	2006	In the nucleus, arsenic, but not phenolic antioxidant tert-butylhydroquinone, dissociated Nrf2 from Keap1 and Cul3 followed by dimerization of Nrf2 with a Maf protein (Maf G/Maf K).	Arsenic	16-23	MAF bZIP transcription factor	Homo sapiens	155-158	
16785233-7	2006	In the nucleus, arsenic, but not phenolic antioxidant tert-butylhydroquinone, dissociated Nrf2 from Keap1 and Cul3 followed by dimerization of Nrf2 with a Maf protein (Maf G/Maf K).	Arsenic	16-23	MAF bZIP transcription factor	Homo sapiens	168-171	
16785233-7	2006	In the nucleus, arsenic, but not phenolic antioxidant tert-butylhydroquinone, dissociated Nrf2 from Keap1 and Cul3 followed by dimerization of Nrf2 with a Maf protein (Maf G/Maf K).	Arsenic	16-23	MAF bZIP transcription factor	Homo sapiens	168-171	
16785233-9	2006	Arsenic substantially increased the ARE occupancy by Nrf2 and Maf.	Arsenic	0-7	MAF bZIP transcription factor	Homo sapiens	62-65	
16487037-0	2006	Induction of endogenous Nrf2/small maf heterodimers by arsenic-mediated stress in placental choriocarcinoma cells.	Arsenic	55-62	MAF bZIP transcription factor	Homo sapiens	35-38	
16785233-11	2006	Our data reveal that arsenic activates the Nrf2/Keap1 signaling pathway through a distinct mechanism from that by antioxidants and suggest an "on-switch" model of Nqo1 transcription in which the binding of Nrf2 x Maf to ARE controls both the basal and inducible expression of Nqo1.	Arsenic	21-28	MAF bZIP transcription factor	Homo sapiens	213-216	
16487037-6	2006	Arsenic also induced the binding of endogenous Nrf2/small Maf DNA-binding complexes to a stress response element (StRE) recognition site.	Arsenic	0-7	MAF bZIP transcription factor	Homo sapiens	58-61	
16487037-9	2006	These results suggest that Nrf2/small Maf heterodimers may play an important role in the response to arsenic-mediated stress in placental cells.	Arsenic	101-108	MAF bZIP transcription factor	Homo sapiens	38-41