PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10828279-8	2000	Chronic As exposures produced 2-10 fold elevation of serum interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha levels, with greater increases seen by repeated injections than by oral exposure, and again, MT-null mice had higher serum cytokines than WT mice after As exposure.	Arsenic	8-10	interleukin 6	Mus musculus	78-124	
24754514-10	2014	Proinflammatory cytokines (IL-6 and TNF-alpha) were upregulated following arsenic treatment as in the case of the LPS stimulated group without alterations in anti-inflammatory IL-10.	Arsenic	74-81	interleukin 6	Mus musculus	27-31	
22488045-0	2012	Arsenic modulates heme oxygenase-1, interleukin-6, and vascular endothelial growth factor expression in endothelial cells: roles of ROS, NF-kappaB, and MAPK pathways.	Arsenic	0-7	interleukin 6	Mus musculus	36-49	
19682479-9	2009	Expression of pro-inflammatory chemokine MCP-1 and cytokine IL-6 and markers of oxidative stress, protein-HNE and protein-MDA adducts were markedly increased in lesions of arsenic-exposed mice.	Arsenic	172-179	interleukin 6	Mus musculus	60-64	
19682479-10	2009	Plasma concentrations of MCP-1, IL-6 and MDA were also significantly elevated in arsenic-exposed mice.	Arsenic	81-88	interleukin 6	Mus musculus	32-36	
18296743-7	2008	Arsenic exposure increased the expression of inflammation genes, such as TNF-alpha, IL-6, iNOS, chemokines, and macrophage inflammatory protein-2.	Arsenic	0-7	interleukin 6	Mus musculus	84-88	
27289040-0	2016	Arsenic-induced dose-dependent modulation of the NF-kappaB/IL-6 axis in thymocytes triggers differential immune responses.	Arsenic	0-7	interleukin 6	Mus musculus	59-63	
26312203-5	2015	Mice exposed to arsenic exhibited significant increased in TNF-alpha (4.3-fold), serum Interleukin-1 beta (threefold), Interleukin-6 (3.8-fold) as compared to controls.	Arsenic	16-23	interleukin 6	Mus musculus	119-132	
22938487-6	2012	Results indicated that Th1 cytokines such as TNF-alpha, IFNgamma, IL12 and the Th2 cytokines such as IL4, IL6, IL10 which were respectively downregulated and upregulated following arsenic induction were more efficiently restored to their near normal levels by T11TS alone in comparison with the combined regimen.	Arsenic	180-187	interleukin 6	Mus musculus	106-109	
19874834-8	2010	The serum levels of interleukin-1beta, interleukin-6 and TNF-alpha were significantly increased in arsenic-exposed groups, while in the arsenic-exposed and jaggery supplemented groups their levels were normal.	Arsenic	99-106	interleukin 6	Mus musculus	39-52	
15781290-10	2005	There was a positive correlation between the hepatic arsenic level and collagen content (r = 0.8007), LPx (r = 0.779) and IL-6 (r = 0.7801).	Arsenic	53-60	interleukin 6	Mus musculus	122-126	
35189519-6	2022	Two inflammatory signalling pathways, i.e., TLR2/MyD88/NF-kappaB and IL-6/STAT-3, were activated, along with inflammatory cell infiltration and the elevated mRNA expression of pro-inflammatory cytokines (TNF-alpha, IL-1beta and IFN-gamma) and myeloperoxidase (MPO) in the gastric tissue of mice exposed to arsenic.	Arsenic	306-313	interleukin 6	Mus musculus	69-73	
35189519-9	2022	The arsenic-mediated gene expression of pro-inflammatory cytokines (TNF-alpha, IL-1beta and IFN-gamma), MPO and IL-6/STAT3 and TLR2/MyD88/NF-kappaB pathways was found down-regulated.	Arsenic	4-11	interleukin 6	Mus musculus	112-116	
29948949-2	2019	Previously, we showed that arsenic (0.38 mg/kg body weight) exposure induces microglial activation and consequently IL-6/TNF-alpha secretion.	Arsenic	27-34	interleukin 6	Mus musculus	116-120	
29948949-6	2019	Higher CD68 staining, increased level of IL-6/TNF-alpha, as well as higher level of IFNgamma, were observed in in vivo arsenic-exposed groups.	Arsenic	119-126	interleukin 6	Mus musculus	41-45	
29948949-10	2019	Finally, intracerebral injection of anti-IFNgamma neutralizing antibody in arsenic-exposed brain reduced microglia activation (IL-6 and TNF-alpha and CD68 expression) and subsequently rescued CD200 level.	Arsenic	75-82	interleukin 6	Mus musculus	127-131	
29948949-11	2019	Taken together, the study showed that arsenic-mediated compromised blood-brain barrier is a major driving force to induce microglial IL-6 and TNF-alpha production through serum IFNgamma leading to CD200 downregulation.	Arsenic	38-45	interleukin 6	Mus musculus	133-137