PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19073887-4 2009 Arsenic, mercury, and nickel cause reduction of transcription of ribosome biogenesis genes, which are under the control of Sfp1, a TORC1-regulated transcriptional activator. Arsenic 0-7 zinc-coordinating transcription factor SFP1 Saccharomyces cerevisiae S288C 123-127 19073887-5 2009 We report that arsenic stress deactivates Sfp1 as it becomes dephosphorylated, dissociates from chromatin, and exits the nucleus. Arsenic 15-22 zinc-coordinating transcription factor SFP1 Saccharomyces cerevisiae S288C 42-46 19073887-6 2009 Curiously, whereas loss of SFP1 function leads to increased arsenic resistance, absence of TOR1 or SCH9 has the opposite effect suggesting that TORC1 has a role beyond down-regulation of Sfp1. Arsenic 60-67 zinc-coordinating transcription factor SFP1 Saccharomyces cerevisiae S288C 27-31