PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35487881-9 2022 After treatment with 5-Aza-2-Dc, the methylation levels of the ABCB1 CpG sites in HepG2 cells significantly decreased, and this was confirmed by pyrosequencing; there was also a significant increase in ABCB1 transcription, which induced a decrease in intracellular tacrolimus concentrations. 5-aza-2-dc 21-31 ATP binding cassette subfamily B member 1 Homo sapiens 63-68 35487881-9 2022 After treatment with 5-Aza-2-Dc, the methylation levels of the ABCB1 CpG sites in HepG2 cells significantly decreased, and this was confirmed by pyrosequencing; there was also a significant increase in ABCB1 transcription, which induced a decrease in intracellular tacrolimus concentrations. 5-aza-2-dc 21-31 ATP binding cassette subfamily B member 1 Homo sapiens 202-207