PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9686926-9 1998 The strong inhibitory effect of PKC theta is accompanied by a molecular weight shift of IRS-1 (183 kDa vs 180 kDa) in the sodium dodecyl sulphate polyacrylamide gel. Sodium Dodecyl Sulfate 122-145 insulin receptor substrate 1 Homo sapiens 88-93 10847581-2 2000 Insulin stimulation elicits serine/threonine phosphorylation of IRS-1, which produces a mobility shift on SDS-PAGE, followed by degradation of IRS-1 after prolonged stimulation. Sodium Dodecyl Sulfate 106-109 insulin receptor substrate 1 Homo sapiens 64-69 22454254-2 2012 The first cloned and characterized member of the IRS family, IRS-1, has a predicted molecular weight of 132 kDa, however, as a result of its extensive serine phosphorylation it separates on a SDS gel as a band of approximately 160-185 kDa. Sodium Dodecyl Sulfate 192-195 insulin receptor substrate 1 Homo sapiens 61-66 8513971-10 1993 When human IRS-1 cDNA was expressed in Chinese hamster ovary cells, the protein migrated between 170,000-180,000 M(r) in sodium dodecyl sulfate-polyacrylamide gel electrophoresis and was rapidly Tyr phosphorylated upon insulin stimulation. Sodium Dodecyl Sulfate 121-143 insulin receptor substrate 1 Homo sapiens 11-16