PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8365410-10 1993 When 125I-IL-6 was chemically cross-linked to the purified srhIL-6R and analyzed by SDS/PAGE, several 125I-IL-6-containing bands were detected, indicating the possible existence of a multimeric structure of the natural IL-6/IL-6R complex. Sodium Dodecyl Sulfate 84-87 interleukin 6 Homo sapiens 10-14 8603813-6 1996 The molecular weight of human HSF was about 42 kDa as estimated by SDS-PAGE. Sodium Dodecyl Sulfate 67-70 interleukin 6 Homo sapiens 30-33 8689424-4 1996 Platelet-rich plasma (PRP) specimens from bolus IL-6-treated patients demonstrated an increased incorporation of actin-binding protein and myosin in the cytoskeletal core (triton insoluble residue) as shown by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) in comparison to control specimens. Sodium Dodecyl Sulfate 210-232 interleukin 6 Homo sapiens 48-52 8689424-4 1996 Platelet-rich plasma (PRP) specimens from bolus IL-6-treated patients demonstrated an increased incorporation of actin-binding protein and myosin in the cytoskeletal core (triton insoluble residue) as shown by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) in comparison to control specimens. Sodium Dodecyl Sulfate 269-272 interleukin 6 Homo sapiens 48-52 12182824-5 2002 An increase in the electrophoretic mobility of secreted hIL-6-HlyA(s) in non-reducing SDS-PAGE, similar to that found for recombinant mature hIL-6, and the absence of such a mobility shift in the intracellular hIL-6-HlyA(s) protein fraction indicated that in hIL-6-HlyA(s) most probably correct intramolecular disulfide bond formation occurred during the secretion step. Sodium Dodecyl Sulfate 86-89 interleukin 6 Homo sapiens 56-61 7538612-5 1995 IL-6 had no direct stimulatory effect on its own, but synergized with IL-1 to induce an increased production of C3 in the culture supernatant and its relative amount was confirmed by SDS-PAGE and immunoblot. Sodium Dodecyl Sulfate 183-186 interleukin 6 Homo sapiens 0-4 7831669-5 1994 Further, PRP incubated with IL-6 showed a dose dependent increase in TXB2 and BTG secretion as measured by RIA and an increased incorporation of actin binding protein, talin, and myosin into the cytoskeletal core (triton insoluble residue) as shown by SDS-PAGE. Sodium Dodecyl Sulfate 252-255 interleukin 6 Homo sapiens 28-32 8365410-10 1993 When 125I-IL-6 was chemically cross-linked to the purified srhIL-6R and analyzed by SDS/PAGE, several 125I-IL-6-containing bands were detected, indicating the possible existence of a multimeric structure of the natural IL-6/IL-6R complex. Sodium Dodecyl Sulfate 84-87 interleukin 6 Homo sapiens 62-66 8365410-10 1993 When 125I-IL-6 was chemically cross-linked to the purified srhIL-6R and analyzed by SDS/PAGE, several 125I-IL-6-containing bands were detected, indicating the possible existence of a multimeric structure of the natural IL-6/IL-6R complex. Sodium Dodecyl Sulfate 84-87 interleukin 6 Homo sapiens 62-66 2332497-7 1990 The 23-25- and 28-30-kD IL-6 species could be readily detected in SDS-PAGE immunoblots performed directly on 10-microliters aliquots of AF from patients with intraamniotic infection. Sodium Dodecyl Sulfate 66-69 interleukin 6 Homo sapiens 24-28 1477074-4 1992 The increase in CEA expression as a result of IL-6 treatment was also observed using SDS-PAGE/Western blot analyses, and subsequent Northern blot analyses revealed concomitant increases in CEA-related mRNA transcripts. Sodium Dodecyl Sulfate 85-88 interleukin 6 Homo sapiens 46-50 1995637-8 1991 Intracellular limited proteolysis of IL-6 could be demonstrated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Sodium Dodecyl Sulfate 67-89 interleukin 6 Homo sapiens 37-41 8354288-5 1993 This complex was stable in SDS and 2-mercaptoethanol at 100 degrees C and was not dissociated by hydroxylamine treatment, indicating the formation of a covalent non-ester bond between the 8-kDa 125I-IL-6-derived peptide and an undetermined acceptor. Sodium Dodecyl Sulfate 27-30 interleukin 6 Homo sapiens 199-203 2033081-5 1991 Elution of the major 85-kDa complex and re-electrophoresis through sodium dodecyl sulfate-PAGE revealed that it represented a heteromeric aggregate of the 25- and 30-kDa IL-6 species; the 45-65-kDa complexes were largely composed of the 25-kDa protein. Sodium Dodecyl Sulfate 67-89 interleukin 6 Homo sapiens 170-174 2310829-6 1990 As judged by sodium dodecyl sulfate-polyacrylamide gel electrophoresis under reducing conditions, IL-6 species of relative molecular mass of 19 to 26 Kd could be specifically immunoprecipitated from supernatants of IL-1-induced monocytes. Sodium Dodecyl Sulfate 13-35 interleukin 6 Homo sapiens 98-102 2584704-7 1989 Treatment with IL-6 also resulted in a dose-dependent reduction of the 17-kDa TNF band revealed by SDS-PAGE after labeling monocytes with [35S]cysteine and immunoprecipitation with anti-TNF mAb. Sodium Dodecyl Sulfate 99-102 interleukin 6 Homo sapiens 15-19 34984290-6 2021 SDS-PAGE analysis of HOCl-treated IL-6 showed little to no fragmentation or aggregation up to 1.75 mM HOCl, suggesting that the modifications induced at concentrations below 1.75 mM took place on the intact protein. Sodium Dodecyl Sulfate 0-3 interleukin 6 Homo sapiens 34-38 32882369-8 2020 In the static RHS, the SDS-treated tissues also released significantly high LDH (82 %; p < 0.05) and significantly lower IL-6 release (p < 0.05), corroborating with the other metabolic levels. Sodium Dodecyl Sulfate 23-26 interleukin 6 Homo sapiens 121-125 2789018-7 1989 Combined immunoprecipitation, immunoblotting, and immunoaffinity chromatography experiments reveal additional IL-6 species with mobilities in sodium dodecyl sulfate-polyacrylamide gel electrophoresis under reducing conditions corresponding to molecular masses 17-19 kDa and 45 kDa, suggesting that this cytokine undergoes further alterations. Sodium Dodecyl Sulfate 142-164 interleukin 6 Homo sapiens 110-114 2649105-5 1989 Immunoaffinity chromatography followed by Western blotting shows that IL-6 species secreted by IL-1 alpha-induced HUVEC are of molecular mass 23-25, 27-30 and 45 kDa as judged by SDS-PAGE under reducing conditions. Sodium Dodecyl Sulfate 179-182 interleukin 6 Homo sapiens 70-74 31408593-0 2019 [Study of the quantity of interleukin-6 by SDS-PAAG electrophoresis and immuno-enzyme analysis in mixed saliva after rinsing the oral cavity with oligonucleotide specific.] Sodium Dodecyl Sulfate 43-46 interleukin 6 Homo sapiens 26-39 31408593-1 2019 The selective properties of a solution of oligonucleotide specific to IL-6 on the concentration of IL-6 in mixed saliva of patients with oral inflammatory processes were studied using SDS-PAGE by electrophoresis and enzyme immunoassay. Sodium Dodecyl Sulfate 184-187 interleukin 6 Homo sapiens 70-74 31408593-3 2019 The ELISA Kit and 20% SDS-PAGE showed the highest sensitivity to determine the concentration of IL-6 in saliva, which should be considered in clinical laboratory practice. Sodium Dodecyl Sulfate 22-25 interleukin 6 Homo sapiens 96-100 22103940-5 2011 In addition, skin irritation induced by an application of sodium dodecyl sulphate resulted in significantly higher lactate dehydrogenase leakage, and interleukin (IL)-6 and IL-8 levels, than in the control model. Sodium Dodecyl Sulfate 58-81 interleukin 6 Homo sapiens 150-168 26263552-15 2016 After accounting for SDS, IL-6 concentrations in young women remained higher after both mental and physical stress. Sodium Dodecyl Sulfate 21-24 interleukin 6 Homo sapiens 26-30 24964617-11 2014 Both non-allergens SDS and IPA significantly induced IL-6 secretion in a dose-dependent manner however SDS cause a higher production levels, approximately 20 times of the control. Sodium Dodecyl Sulfate 19-22 interleukin 6 Homo sapiens 53-57 19477472-6 2009 After 9 months of treatment, obese children with lowered BMI SD score (SDS-BMI) displayed a significant decrease in insulin (P = .011), homeostasis model assessment of insulin resistance (P = .012), CRP (P = .006), and interleukin-6 (IL-6) (P = .045) levels compared with obese children with stable SDS-BMI; they also displayed a nonsignificant drop in sICAM levels. Sodium Dodecyl Sulfate 71-74 interleukin 6 Homo sapiens 219-232 19477472-6 2009 After 9 months of treatment, obese children with lowered BMI SD score (SDS-BMI) displayed a significant decrease in insulin (P = .011), homeostasis model assessment of insulin resistance (P = .012), CRP (P = .006), and interleukin-6 (IL-6) (P = .045) levels compared with obese children with stable SDS-BMI; they also displayed a nonsignificant drop in sICAM levels. Sodium Dodecyl Sulfate 71-74 interleukin 6 Homo sapiens 234-238 19477472-7 2009 Similarly, obese children with lowered SDS-BMI displayed a decrease in CRP (P = .005) and IL-6 (P = .065) compared with baseline levels before treatment. Sodium Dodecyl Sulfate 39-42 interleukin 6 Homo sapiens 90-94 19477472-8 2009 In the total obese group, changes in SDS-BMI correlated positively with changes in CRP (P = .035), IL-6 (P = .027), and sICAM-1 (P = .038) levels. Sodium Dodecyl Sulfate 37-40 interleukin 6 Homo sapiens 99-103 19477472-9 2009 Only SDS-BMI was an independent predictive factor for CRP (P = .031), IL-6 (P = .027), and sICAM-1 (P = .033). Sodium Dodecyl Sulfate 5-8 interleukin 6 Homo sapiens 70-74