PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33917915-1	2021	Protocatechuic aldehyde (PA) is a naturally occurring phenolic compound that is a potent inhibitor of mushroom tyrosinase.	protocatechualdehyde	25-27	tyrosinase	Mus musculus	111-121	
33917915-4	2021	We first predicted the 3D structure of tyrosinase and used a molecular docking algorithm to simulate binding between tyrosinase and PA.	protocatechualdehyde	132-134	tyrosinase	Mus musculus	39-49	
33917915-4	2021	We first predicted the 3D structure of tyrosinase and used a molecular docking algorithm to simulate binding between tyrosinase and PA.	protocatechualdehyde	132-134	tyrosinase	Mus musculus	117-127	
33917915-6	2021	Furthermore, PA significantly decreased alpha-MSH-induced intracellular tyrosinase activity and melanin content in a dose-dependent manner.	protocatechualdehyde	13-15	tyrosinase	Mus musculus	72-82	
33917915-7	2021	PA also inhibited key melanogenic proteins such as tyrosinase, tyrosinase-related protein 1 (TRP-1), and TRP-2 in alpha-MSH-stimulated B16F10 cells.	protocatechualdehyde	0-2	tyrosinase	Mus musculus	51-61