PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12942110-10 2003 The AUC(0-10 h) of uracil on day 5 was 252+/-60 ng h ml(-1) with PVI of 5-FU and 12 582+/-3060 ng h ml(-1) with S-1. Uracil 19-25 proteasome 26S subunit, non-ATPase 1 Homo sapiens 112-115 12942110-11 2003 The AUC(0-10 h) of FBAL was markedly lower and plasma uracil concentrations were significantly higher for S-1 than for PVI of 5-FU, clearly demonstrating the effect of DPD inhibition. Uracil 54-60 proteasome 26S subunit, non-ATPase 1 Homo sapiens 106-109 19921195-0 2010 Can the 2-(13)C-uracil breath test be used to predict the effect of the antitumor drug S-1? Uracil 16-22 proteasome 26S subunit, non-ATPase 1 Homo sapiens 87-90 21378348-11 2011 Following single- and multiple-dose administration of S-1, plasma concentrations of uracil returned to baseline levels within approximately 48 h of dosing, indicating reversibility of DPD inhibition by CDHP. Uracil 84-90 proteasome 26S subunit, non-ATPase 1 Homo sapiens 54-57 20500514-8 2010 These results suggest that the preferential anti-LNM activity of S-1 compared with UFT/LV against high-DPD COLM-5 tumors is due to the higher DPD inhibitory activity of 5-chloro-2, 4-dihydroxypyrimidine (CDHP) present in S-1 than uracil in UFT. Uracil 230-236 proteasome 26S subunit, non-ATPase 1 Homo sapiens 65-68 16897970-9 2006 The AUC0-10h of uracil on day 5 was 252 +/- 60 ng x hr/ml with PVI of 5-FU and 12,582 +/- 3,060 ng x hr/ml with S-1. Uracil 16-22 proteasome 26S subunit, non-ATPase 1 Homo sapiens 112-115 16897970-10 2006 The AUC0-10h of FBAL was markedly lower and plasma uracil concentrations were significantly higher for S-1 than for PVI of 5-FU, clearly demonstrating the effect of DPD inhibition. Uracil 51-57 proteasome 26S subunit, non-ATPase 1 Homo sapiens 103-106