PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21654193-4 2011 Decitabine, and to a lesser degree azacitidine, induced the activation of checkpoint kinases Chk-1 and Chk-2 and the phosphorylation of the DDR-sensor H2AX. Azacitidine 35-46 checkpoint kinase 2 Homo sapiens 103-108 15153943-5 2004 Chromatin-immunoprecipitation (Chip) assays revealed that treatment of HL cells with TsA, SB or 5Aza-dC resulted in increased levels of acetylated histones H3 and H4, and decreased levels of dimethylated H3 lysine 9 at the Chk2 promoter. Azacitidine 96-100 checkpoint kinase 2 Homo sapiens 223-227