PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31020710-9 2019 Expression of phosphorylated AMPK was increased and that of phosphorylated mammalian target of rapamycin (mTOR) was decreased after exposure to tHA plus metformin. tha 144-147 mechanistic target of rapamycin kinase Homo sapiens 75-104 31020710-9 2019 Expression of phosphorylated AMPK was increased and that of phosphorylated mammalian target of rapamycin (mTOR) was decreased after exposure to tHA plus metformin. tha 144-147 mechanistic target of rapamycin kinase Homo sapiens 106-110 31020710-10 2019 Taken together, our results demonstrate that tHA, combined with metformin, increases the viability of hPDLSCs via the AMPK/mTOR signaling pathway by regulating autophagy and further improving the osteogenic effect. tha 45-48 mechanistic target of rapamycin kinase Homo sapiens 123-127