PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8561506-1 1996 We have been able to demonstrate that cytochrome b4 interacts closely with cytochrome P450 in the microsomal membrane, and that substrates can serve to order the interaction: Using the water-soluble carbodiimide EDC we could crosslink cytochrome b5 and CYP2B4 in microsomes from phenobarbital-treated rabbits and cytochrome b5 and CYP1A2 in microsomes from beta-naphthoflavone-treated animals. Carbodiimides 199-211 cytochrome P450 2B4 Oryctolagus cuniculus 253-259 1416971-11 1992 Complex formation between the NADPH-cytochrome P450 reductase and cytochrome P450 LM2 monomers was not detected by recording the difference binding spectra of the reductase monomers with LM2 monomers or by treatment the mixture of the monomers of the proteins with the crosslinking reagent, water-soluble carbodiimide. Carbodiimides 305-317 cytochrome P450 2B4 Oryctolagus cuniculus 66-85