PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31285371-10	2019	Inhibition of TGFbeta1 by SB431542, ERK by selumetinib, or HIF1alpha by YC-1 efficiently overcame platinum resistance both in vitro and in vivo The results from clinical samples confirm activation of the ERK/PHD2/HIF1alpha axis in patients with PROC, correlating highly with poor prognoses for patients.Conclusions: HIF1alpha stabilization is regulated by TGFbeta1/ERK/PHD2 axis in PROC.	Platinum	98-106	latent transforming growth factor beta binding protein 1	Homo sapiens	356-364	
31285371-9	2019	Significantly, ERK/PHD2 signaling in PROC cells is dependent on TGFbeta1, promoting platinum resistance by stabilizing HIF1alpha.	Platinum	84-92	latent transforming growth factor beta binding protein 1	Homo sapiens	64-72	
31285371-10	2019	Inhibition of TGFbeta1 by SB431542, ERK by selumetinib, or HIF1alpha by YC-1 efficiently overcame platinum resistance both in vitro and in vivo The results from clinical samples confirm activation of the ERK/PHD2/HIF1alpha axis in patients with PROC, correlating highly with poor prognoses for patients.Conclusions: HIF1alpha stabilization is regulated by TGFbeta1/ERK/PHD2 axis in PROC.	Platinum	98-106	latent transforming growth factor beta binding protein 1	Homo sapiens	14-22