PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19035296-0 2008 Inotodiol, a lanostane triterpenoid, from Inonotus obliquus inhibits cell proliferation through caspase-3-dependent apoptosis. inotodiol 0-9 caspase 3 Mus musculus 96-105 19035296-7 2008 DNA fragmentation and caspase-3/7 activation were observed in the P388 cells treated with inotodiol (30 microM). inotodiol 90-99 caspase 3 Mus musculus 22-31 19035296-8 2008 A caspase-3 inhibitor, DEVD-CHO (N-acetyl-Asp-Glu-Val-Asp-al, 100 microM) partially inhibited the DNA fragmentation and growth-inhibition induced by inotodiol. inotodiol 149-158 caspase 3 Mus musculus 2-11 19035296-10 2008 CONCLUSION: Inotodiol inhibits cell proliferation through apoptosis induction by activating caspase-3. inotodiol 12-21 caspase 3 Mus musculus 92-101