PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10746939-5	2000	In this report we demonstrated that the commonly used 2-chloro-s-triazine herbicides atrazine, simazine, and propazine dose-dependently (0-30 microM) induced aromatase (CYP19) activity to an apparent maximum of about 2.5-fold in H295R cells.	Atrazine	85-93	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	169-174	
26464060-7	2016	In H295R cells, atrazine concentration-dependently increased PII- and I.3-mediated CYP19 expression and aromatase catalytic activity.	Atrazine	16-24	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	83-88	
26464060-7	2016	In H295R cells, atrazine concentration-dependently increased PII- and I.3-mediated CYP19 expression and aromatase catalytic activity.	Atrazine	16-24	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	104-113	
26464060-9	2016	In HUVEC cells, atrazine slightly induced overall (promoter-indistinct) CYP19 expression (30 microM) and aromatase activity (>= 3 microM), without increasing I.1 promoter activity.	Atrazine	16-24	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	72-77	
26464060-9	2016	In HUVEC cells, atrazine slightly induced overall (promoter-indistinct) CYP19 expression (30 microM) and aromatase activity (>= 3 microM), without increasing I.1 promoter activity.	Atrazine	16-24	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	105-114	
24486430-6	2014	Atrazine and prochloraz had cell-type specific effects on CYP19 activity and estrogen production in co-culture.	Atrazine	0-8	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	58-63	
24486430-7	2014	Atrazine induced CYP19 activity and estrogen production in H295R cells only, but did not affect overall estrogen production in co-culture, whereas prochloraz inhibited CYP19 activity exclusively in BeWo cells and reduced estrogen production in co-culture by almost 90%.	Atrazine	0-8	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	17-22	
26464060-5	2016	Exposure to certain pesticides, such as atrazine, is associated with increased CYP19 expression, but little is known about the effects of neonicotinoid insecticides on CYP19.	Atrazine	40-48	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	79-84	
26464060-6	2016	We developed sensitive and robust RT-qPCR methods to detect the promoter-specific expression of CYP19 in human adrenocortical carcinoma (H295R) and primary umbilical vein endothelial (HUVEC) cells, and determined the potential promoter-specific disruption of CYP19 expression by atrazine and the commonly used neonicotinoids imidacloprid, thiacloprid, and thiamethoxam.	Atrazine	279-287	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	96-101