PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22342499-0	2012	Protective role of endogenous catalase in baseline and phenytoin-enhanced neurodevelopmental and behavioral deficits initiated in utero and in aged mice.	Phenytoin	55-64	catalase	Mus musculus	30-38	
22342499-7	2012	Endogenous catalase plays an important gender-dependent neuroprotective role in utero and in aged mice, and reduces neurodevelopmental effects of phenytoin.	Phenytoin	146-155	catalase	Mus musculus	11-19	
21478259-4	2011	Compared to wild-type (WT) catalase-normal controls, both untreated and phenytoin-exposed aCat mice exhibited a 30% increase in embryonic DNA oxidation and a >2-fold increase in embryopathies, both of which were completely blocked by protein therapy with exogenous catalase.	Phenytoin	72-81	catalase	Mus musculus	27-35	
21478259-4	2011	Compared to wild-type (WT) catalase-normal controls, both untreated and phenytoin-exposed aCat mice exhibited a 30% increase in embryonic DNA oxidation and a >2-fold increase in embryopathies, both of which were completely blocked by protein therapy with exogenous catalase.	Phenytoin	72-81	catalase	Mus musculus	268-276	
21252394-4	2011	Phenytoin was embryopathic in all strains without altering catalase activity but less so in the WT embryos for the aCat and hCat strains, which exhibited about half the catalase activity of CD-1 embryos.	Phenytoin	0-9	catalase	Mus musculus	169-177	
21252394-6	2011	Among aCat embryos exposed to phenytoin, embryopathies increased with decreasing catalase activity and were completely blocked by addition of exogenous catalase, which increased embryonic catalase activity to WT levels.	Phenytoin	30-39	catalase	Mus musculus	81-89	
21252394-6	2011	Among aCat embryos exposed to phenytoin, embryopathies increased with decreasing catalase activity and were completely blocked by addition of exogenous catalase, which increased embryonic catalase activity to WT levels.	Phenytoin	30-39	catalase	Mus musculus	152-160	
21252394-6	2011	Among aCat embryos exposed to phenytoin, embryopathies increased with decreasing catalase activity and were completely blocked by addition of exogenous catalase, which increased embryonic catalase activity to WT levels.	Phenytoin	30-39	catalase	Mus musculus	152-160	
9895216-2	1999	This in vivo study in pregnant CD-1 mice evaluated whether maternal administration of the antioxidative enzymes superoxide dismutase (SOD) and/or catalase conjugated with polyethylene glycol (PEG) could reduce phenytoin teratogenicity.	Phenytoin	210-219	catalase	Mus musculus	146-154	
9013124-11	1997	Addition of the reducing agent dithiothreitol, or SOD or catalase, decreased protein oxidation in phenytoin-exposed embryos.	Phenytoin	98-107	catalase	Mus musculus	57-65	
7623765-0	1995	Phenytoin-initiated DNA oxidation in murine embryo culture, and embryo protection by the antioxidative enzymes superoxide dismutase and catalase: evidence for reactive oxygen species-mediated DNA oxidation in the molecular mechanism of phenytoin teratogenicity.	Phenytoin	236-245	catalase	Mus musculus	136-144	
7623765-9	1995	Superoxide dismutase and catalase virtually eliminated phenytoin-initiated 8-OH-2"-dG formation and reduced or completely eliminated all phenytoin-initiated dysmorphological anomalies (p < 0.05).	Phenytoin	55-64	catalase	Mus musculus	25-33	
7623765-9	1995	Superoxide dismutase and catalase virtually eliminated phenytoin-initiated 8-OH-2"-dG formation and reduced or completely eliminated all phenytoin-initiated dysmorphological anomalies (p < 0.05).	Phenytoin	137-146	catalase	Mus musculus	25-33