PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25687583-4	2016	The R and S form of thiophene based pyrazolines-carboxamides showed a binding energy and inhibition constant between 7.93 to -8.76 and 1.54 to 0.38 muM toward MAO-A and -6.39 to -8.51 and 20.84 to 0.57 muM toward MAO-B respectively.	Thiophenes	20-29	latexin	Homo sapiens	148-151	
27005608-6	2016	The best compound, with potent and selective cytotoxicity (IC50 = 12.51 muM in comparison with the value 10.84 muM of paclitaxel), contains a phenothiazine moiety on ring A and a thiophene heterocycle on ring B.	Thiophenes	179-188	latexin	Homo sapiens	72-75	
27005608-6	2016	The best compound, with potent and selective cytotoxicity (IC50 = 12.51 muM in comparison with the value 10.84 muM of paclitaxel), contains a phenothiazine moiety on ring A and a thiophene heterocycle on ring B.	Thiophenes	179-188	latexin	Homo sapiens	111-114	
25687583-4	2016	The R and S form of thiophene based pyrazolines-carboxamides showed a binding energy and inhibition constant between 7.93 to -8.76 and 1.54 to 0.38 muM toward MAO-A and -6.39 to -8.51 and 20.84 to 0.57 muM toward MAO-B respectively.	Thiophenes	20-29	latexin	Homo sapiens	202-205	
21893371-6	2011	Finally replacement of the thiophene ring with a bioisosteric phenyl ring further improved the inhibitory activity as seen in compounds 21a [IC(50) = 5.2 muM] and 24a [IC(50) = 2.4 muM].	Thiophenes	27-36	latexin	Homo sapiens	154-157	
21893371-6	2011	Finally replacement of the thiophene ring with a bioisosteric phenyl ring further improved the inhibitory activity as seen in compounds 21a [IC(50) = 5.2 muM] and 24a [IC(50) = 2.4 muM].	Thiophenes	27-36	latexin	Homo sapiens	181-184