PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12113803-0 2002 Synthesis and bioactivities of novel bicyclic thiophenes and 4,5,6,7-tetrahydrothieno[2,3-c]pyridines as inhibitors of tumor necrosis factor-alpha (TNF-alpha) production. Thiophenes 46-56 tumor necrosis factor Rattus norvegicus 119-146 12113803-0 2002 Synthesis and bioactivities of novel bicyclic thiophenes and 4,5,6,7-tetrahydrothieno[2,3-c]pyridines as inhibitors of tumor necrosis factor-alpha (TNF-alpha) production. Thiophenes 46-56 tumor necrosis factor Rattus norvegicus 148-157 12113803-1 2002 We synthesized bicyclic thiophenes and 4,5,6,7-tetrahydrothieno[2,3-c]pyridine derivatives, and evaluated for their ability to inhibit LPS-stimulated production of TNF-alpha. Thiophenes 24-34 tumor necrosis factor Rattus norvegicus 164-173