PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7576100-7	1995	In immunoinhibition analysis, anti-Cyp2a-5 antibody inhibited rat nasal COH activity and aflatoxin B1 (AFB1) metabolism completely.	Aflatoxin B1	89-101	cytochrome P450, family 2, subfamily a, polypeptide 5	Mus musculus	35-42	
21395539-2	2011	Since CYP2A5 metabolizes various important xenobiotics including nicotine and pro-carcinogens such as nitrosamines and aflatoxin B(1), altered gene expression could affect tobacco addiction, hepatotoxicity and hepatocarcinogenesis.	Aflatoxin B1	119-130	cytochrome P450, family 2, subfamily a, polypeptide 5	Mus musculus	6-12	
9726815-1	1998	Cytochrome P450 (CYP) 2A5 is involved in the metabolism of carcinogens like aflatoxin B1 and N-nitrosodiethylamine (NDEA), and CYP2A5 levels are increased in some pathological states of the liver (e.g., infectious hepatitis and porphyria).	Aflatoxin B1	76-88	cytochrome P450, family 2, subfamily a, polypeptide 5	Mus musculus	0-25	
7576100-7	1995	In immunoinhibition analysis, anti-Cyp2a-5 antibody inhibited rat nasal COH activity and aflatoxin B1 (AFB1) metabolism completely.	Aflatoxin B1	103-107	cytochrome P450, family 2, subfamily a, polypeptide 5	Mus musculus	35-42	
7576100-10	1995	When coumarin instead of anti-Cyp2a-5 antibody was used, a strong but variable inhibition of the nasal metabolism of AFB1, NDEA, and NNK was seen.	Aflatoxin B1	117-121	cytochrome P450, family 2, subfamily a, polypeptide 5	Mus musculus	30-37	
28298240-1	2017	BACKGROUND: Cytochrome P450 2A5 (Cyp2a5), a mouse enzyme orthologous of human CYP2A6, catalyzes a number of toxicologically important reactions, including the metabolism of nicotine, aflatoxin B1, and several other xeno- and endobiotics.	Aflatoxin B1	183-195	cytochrome P450, family 2, subfamily a, polypeptide 5	Mus musculus	33-39	
7916996-3	1994	We found that one, and perhaps more, hamster liver cytochrome P450 (CYP) isozymes immunorelated to mouse CYP2A5 contributed up to 50 or 60% of the hepatic aflatoxin B1 (AFB) and N-nitrosodiethylamine (NDEA) metabolism, respectively.	Aflatoxin B1	155-167	cytochrome P450, family 2, subfamily a, polypeptide 5	Mus musculus	105-111	
7916996-3	1994	We found that one, and perhaps more, hamster liver cytochrome P450 (CYP) isozymes immunorelated to mouse CYP2A5 contributed up to 50 or 60% of the hepatic aflatoxin B1 (AFB) and N-nitrosodiethylamine (NDEA) metabolism, respectively.	Aflatoxin B1	169-172	cytochrome P450, family 2, subfamily a, polypeptide 5	Mus musculus	105-111	
7916996-6	1994	Immunohistochemical analysis of AFB-DNA adducts in the livers of O. viverrini-infested hamsters treated with AFB showed that the highest levels of adducts were found in the regions of liver where hepatocellular expression of enzymes detectable by anti-CYP2A5 antibody is induced.	Aflatoxin B1	109-112	cytochrome P450, family 2, subfamily a, polypeptide 5	Mus musculus	252-258	
7867691-2	1994	The reconstituted monooxygenase complex with CYP2A5 purified from yeast cell microsomes produced epoxide at a rate of 17.2 nmol/min per nmol P450 in the presence of 50 microM aflatoxin B1 while CYP2A4 had about 10% and P4507 alpha only 1.5% of this activity.	Aflatoxin B1	175-187	cytochrome P450, family 2, subfamily a, polypeptide 5	Mus musculus	45-51	
7867691-6	1994	Coumarin an inhibitor for CYP2A4 and a substrate for CYP2A5 diminished the toxicity of aflatoxin B1 in a dose-dependent manner for these recombinant yeast cells.	Aflatoxin B1	87-99	cytochrome P450, family 2, subfamily a, polypeptide 5	Mus musculus	53-59	
7867691-8	1994	The data also indicate that mouse CYP2A5 and its counterpart in other species could have a significant role in aflatoxin B1 toxicity in organs where it is expressed at high levels.	Aflatoxin B1	111-123	cytochrome P450, family 2, subfamily a, polypeptide 5	Mus musculus	34-40	
28298240-1	2017	BACKGROUND: Cytochrome P450 2A5 (Cyp2a5), a mouse enzyme orthologous of human CYP2A6, catalyzes a number of toxicologically important reactions, including the metabolism of nicotine, aflatoxin B1, and several other xeno- and endobiotics.	Aflatoxin B1	183-195	cytochrome P450, family 2, subfamily a, polypeptide 5	Mus musculus	12-31	
22497566-1	2013	The mouse hepatic cytochrome P450 (CYP) 2A5 and its human orthologue CYP2A6 catalyse the metabolism of a number of drugs and toxins, such as halothane and aflatoxin B1.	Aflatoxin B1	155-167	cytochrome P450, family 2, subfamily a, polypeptide 5	Mus musculus	18-43