PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3905406-11 1985 Whereas newly synthesized cathepsin D was found in the lysosomes 1 h after synthesis, alpha-glucosidase was detected only after 2-4 h. When a pulse-chase experiment was carried out in the presence of 10 mM NH4Cl there was a complete inhibition of the transport of cathepsin D and a partial inhibition of that of alpha-glucosidase to the lysosomes. Ammonium Chloride 206-211 sucrase-isomaltase Homo sapiens 86-103 1324837-9 1992 Enzyme activity measurements and immunoprecipitation of metabolically labeled cells showed that incubation with NH4Cl leads to an enhanced secretion of these enzymes into the basolateral medium, but has no effect on the basolateral secretion of alpha-glucosidase. Ammonium Chloride 112-117 sucrase-isomaltase Homo sapiens 245-262 3905406-11 1985 Whereas newly synthesized cathepsin D was found in the lysosomes 1 h after synthesis, alpha-glucosidase was detected only after 2-4 h. When a pulse-chase experiment was carried out in the presence of 10 mM NH4Cl there was a complete inhibition of the transport of cathepsin D and a partial inhibition of that of alpha-glucosidase to the lysosomes. Ammonium Chloride 206-211 sucrase-isomaltase Homo sapiens 312-329 6761145-2 1982 When the labelling was carried out for 6-12 h in the presence of NH4Cl, the labelling of secreted alpha-glucosidase relative to that of secreted cathepsin D in fibroblasts from patients with the late-onset form of Pompe"s disease was less than 15% of that in fibroblasts from control persons. Ammonium Chloride 65-70 sucrase-isomaltase Homo sapiens 98-115