PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8048566-5 1994 Decreasing intracellular pH (pHi) by the NH4Cl pulse method showed similar results, suggesting a possible regulatory role of pHi on cotransport activity. Ammonium Chloride 41-46 glucose-6-phosphate isomerase Oryctolagus cuniculus 29-32 10443458-4 1999 In contrast, when pHi was increased by simultaneous addition of NH4Cl, methylamine or monensin, aggregation in response to a low concentration of thrombin, U46619, arachidonic acid or A23187 was enhanced significantly. Ammonium Chloride 64-69 glucose-6-phosphate isomerase Oryctolagus cuniculus 18-21 10443458-5 1999 The enhancing effect of NH4Cl was lowered by prolonged incubation with NH4Cl, by which the increased pHi was improved concomitantly. Ammonium Chloride 24-29 glucose-6-phosphate isomerase Oryctolagus cuniculus 101-104 10443458-5 1999 The enhancing effect of NH4Cl was lowered by prolonged incubation with NH4Cl, by which the increased pHi was improved concomitantly. Ammonium Chloride 71-76 glucose-6-phosphate isomerase Oryctolagus cuniculus 101-104 9516235-11 1998 DBI also reduced by approximately 40% the rate of pHi recovery in cells acidified by an ammonium chloride (20 mM) prepulse; a reduction in pHi recovery rate was also caused by ACTZ and amiloride. Ammonium Chloride 88-105 glucose-6-phosphate isomerase Oryctolagus cuniculus 50-53 9374657-10 1997 Bafilomycin A1 slowed the pHi increase after an NH4Cl (10 mM) prepulse. Ammonium Chloride 48-53 glucose-6-phosphate isomerase Oryctolagus cuniculus 26-29 9156340-6 1997 Changes in pHi determined with the fluorescence multi-well plate reader after the addition and removal of NH4Cl or sodium lactate were comparable to changes in cells analyzed with a digitized fluorescence imaging system. Ammonium Chloride 106-111 glucose-6-phosphate isomerase Oryctolagus cuniculus 11-14 8780258-5 1996 K-dependent pHi recovery (5 mM K, 140 mM N-methyl-D-glucamine) was monitored in response to a pulse of NH4Cl (10 mM). Ammonium Chloride 103-108 glucose-6-phosphate isomerase Oryctolagus cuniculus 12-15 8780258-8 1996 Luminal K-dependent pHi recovery was monitored in response to an acute pulse of NH4Cl in individual peanut lectin agglutinin (PNA)-binding ICs. Ammonium Chloride 80-85 glucose-6-phosphate isomerase Oryctolagus cuniculus 20-23 7818858-2 1994 pHi was modified with ammonium chloride (NH4Cl) and propionate. Ammonium Chloride 22-39 glucose-6-phosphate isomerase Oryctolagus cuniculus 0-3 7818858-2 1994 pHi was modified with ammonium chloride (NH4Cl) and propionate. Ammonium Chloride 41-46 glucose-6-phosphate isomerase Oryctolagus cuniculus 0-3 7485599-4 1995 Control resting pHi (7.1) and acidification in response to NH4Cl pulse (minimum pHi, 6.6) were essentially the same in snake tubules with oil-filled lumens or perfused lumens and in rabbit S2 proximal tubules with oil-filled lumens. Ammonium Chloride 59-64 glucose-6-phosphate isomerase Oryctolagus cuniculus 80-83 1504097-5 1992 Exposure to NH4Cl resulted in an initial intracellular acidification of the TALH SVE.1 cells, followed by a recovery to the initial steady-state pHi value. Ammonium Chloride 12-17 glucose-6-phosphate isomerase Oryctolagus cuniculus 145-148 1329529-9 1992 When cells were acidified (pHi 6.3-7.0) using a NH4Cl (20 mM) pulse technique, pHi was rapidly restored toward neutrality in the presence of a HCO3(-)-free external Na+ concentration ([Na+]o)-containing solution (pH units/min = 0.26 +/- 0.12; n = 8). Ammonium Chloride 48-53 glucose-6-phosphate isomerase Oryctolagus cuniculus 27-30 1329529-9 1992 When cells were acidified (pHi 6.3-7.0) using a NH4Cl (20 mM) pulse technique, pHi was rapidly restored toward neutrality in the presence of a HCO3(-)-free external Na+ concentration ([Na+]o)-containing solution (pH units/min = 0.26 +/- 0.12; n = 8). Ammonium Chloride 48-53 glucose-6-phosphate isomerase Oryctolagus cuniculus 79-82 8184895-7 1994 To determine whether inhibition of Ca2+ absorption results from intracellular acidification, pHi was lowered using an NH4Cl pulse while extracellular pH was kept constant. Ammonium Chloride 118-123 glucose-6-phosphate isomerase Oryctolagus cuniculus 93-96 8184895-7 1994 To determine whether inhibition of Ca2+ absorption results from intracellular acidification, pHi was lowered using an NH4Cl pulse while extracellular pH was kept constant. Ammonium Chloride 118-123 glucose-6-phosphate isomerase Oryctolagus cuniculus 93-95 3446806-19 1987 During 10 min applications of 30 mM-NH4Cl (isosmotically substituted for NaCl) the pHi rose; during subsequent NH4Cl removal it fell below control values. Ammonium Chloride 35-41 glucose-6-phosphate isomerase Oryctolagus cuniculus 83-86 1659205-5 1991 In both the absence and presence of ouabain, pHi fell transiently and then recovered after removal of NH4Cl. Ammonium Chloride 102-107 glucose-6-phosphate isomerase Oryctolagus cuniculus 45-48 2843231-3 1988 After intracellular acidification induced by the NH4Cl-prepulse technique, there was a sodium-dependent pHi recovery towards the normal steady-state pHi. Ammonium Chloride 49-54 glucose-6-phosphate isomerase Oryctolagus cuniculus 104-107 2843231-3 1988 After intracellular acidification induced by the NH4Cl-prepulse technique, there was a sodium-dependent pHi recovery towards the normal steady-state pHi. Ammonium Chloride 49-54 glucose-6-phosphate isomerase Oryctolagus cuniculus 149-152 2843231-7 1988 There was a dose-dependent inhibition of pHi recovery after NH4Cl prepulse by amiloride with an IC50 of about 15 microM. Ammonium Chloride 60-65 glucose-6-phosphate isomerase Oryctolagus cuniculus 41-44 1314849-4 1992 This pHi recovery rate was similar in chronic acidosis induced by NH4Cl loading, but it was enhanced (+111%) by treatment with deoxycorticosterone acetate (DOCA). Ammonium Chloride 66-71 glucose-6-phosphate isomerase Oryctolagus cuniculus 5-8 2260683-2 1990 Initial pHi recovery rates (dpHi/dt, pH unit/s x 10(3)) after intracellular acid load made by NH4Cl prepulse were determined. Ammonium Chloride 94-99 glucose-6-phosphate isomerase Oryctolagus cuniculus 8-11 2175547-5 1990 When normoxic hearts were acidified using a 20 mM NH4Cl prepulse technique, pHi rapidly fell from 7.27 +/- 0.24 to 6.63 +/- 0.12 but returned to 7.07 +/- 0.10 within 20 min, while Na uptake was similar in rate and magnitude to that observed during hypoxia (24.5 +/- 13.4 to 132.1 +/- 17.7 meq/kg dry wt). Ammonium Chloride 50-55 glucose-6-phosphate isomerase Oryctolagus cuniculus 76-79 2854165-10 1988 When pHi was acutely decreased to 5.87 +/- 0.02 following NH4Cl removal (lumen, bath), pHi failed to recover in the absence of Na+ (lumen, bath). Ammonium Chloride 58-63 glucose-6-phosphate isomerase Oryctolagus cuniculus 5-8 2888787-6 1987 After a brief exposure to 20 mM NH4Cl, pHi fell by approximately 0.7 and recovered at a rate of 0.89 +/- 0.15 pH/min in the nominal absence of Na+, HCO3-, organic anions, and SO4(2-) (lumen, bath). Ammonium Chloride 32-37 glucose-6-phosphate isomerase Oryctolagus cuniculus 39-42 3446806-19 1987 During 10 min applications of 30 mM-NH4Cl (isosmotically substituted for NaCl) the pHi rose; during subsequent NH4Cl removal it fell below control values. Ammonium Chloride 36-41 glucose-6-phosphate isomerase Oryctolagus cuniculus 83-86 3446806-20 1987 In the least inhibited tissues the total pHi excursion between NH4Cl applications and removals was 0.5 unit. Ammonium Chloride 63-68 glucose-6-phosphate isomerase Oryctolagus cuniculus 41-44 3446806-23 1987 From the direct measurement of pHi reported in this study, it is concluded that the vascular tone changes brought about by NH4Cl application and withdrawal may be attributed to the alteration of pHi. Ammonium Chloride 123-128 glucose-6-phosphate isomerase Oryctolagus cuniculus 31-34 3446806-23 1987 From the direct measurement of pHi reported in this study, it is concluded that the vascular tone changes brought about by NH4Cl application and withdrawal may be attributed to the alteration of pHi. Ammonium Chloride 123-128 glucose-6-phosphate isomerase Oryctolagus cuniculus 195-198 2418058-8 1986 When cells were acidified by exposure to acetate salts or by abrupt withdrawal of ammonium chloride, they exhibited pHi recovery to the resting pHi over a 5-min time-course. Ammonium Chloride 82-99 glucose-6-phosphate isomerase Oryctolagus cuniculus 116-119 2418058-8 1986 When cells were acidified by exposure to acetate salts or by abrupt withdrawal of ammonium chloride, they exhibited pHi recovery to the resting pHi over a 5-min time-course. Ammonium Chloride 82-99 glucose-6-phosphate isomerase Oryctolagus cuniculus 144-147