PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26025416-3	2015	In K-562 tumor cell line, YTX induces apoptosis and autophagy after 24 and 48 h of incubation, respectively, and the toxin carries out its action through the phosphodiesterase 4A (PDE4A).	yessotoxin	26-29	phosphodiesterase 4A	Homo sapiens	158-178	
26025416-3	2015	In K-562 tumor cell line, YTX induces apoptosis and autophagy after 24 and 48 h of incubation, respectively, and the toxin carries out its action through the phosphodiesterase 4A (PDE4A).	yessotoxin	26-29	phosphodiesterase 4A	Homo sapiens	180-185	
22807343-11	2012	Furthermore, YTX-dependent Ca(2+) pools depletion was abolished by cAMP analogue (dibutyryl cAMP), phosphodiesterase-4 (PDE4) inhibitor (rolipram), protein kinase A inhibitor (H89) and oxidative phosphorylation uncoupler carbonyl cyanide p-(trifluoromethoxy) (FCCP) treatments.	yessotoxin	13-16	phosphodiesterase 4A	Homo sapiens	99-118	
22807343-11	2012	Furthermore, YTX-dependent Ca(2+) pools depletion was abolished by cAMP analogue (dibutyryl cAMP), phosphodiesterase-4 (PDE4) inhibitor (rolipram), protein kinase A inhibitor (H89) and oxidative phosphorylation uncoupler carbonyl cyanide p-(trifluoromethoxy) (FCCP) treatments.	yessotoxin	13-16	phosphodiesterase 4A	Homo sapiens	120-124	
25576684-12	2015	In summary, after 48 h YTX treatment PDE4A-dependent autophagy, as non-apoptotic programmed cell death, is activated.	yessotoxin	23-26	phosphodiesterase 4A	Homo sapiens	37-42