PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32648334-1 2021 This phase 1 study characterized the effect of multiple doses of upadacitinib, an oral Janus kinase 1 selective inhibitor, on the pharmacokinetics of the cytochrome P450 (CYP) 2B6 substrate bupropion. Bupropion 190-199 Janus kinase 1 Homo sapiens 87-101