PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14604466-7	2003	Rifampicin (20 microM) increased CYP2E1 protein by 2.1 fold, while 10 microM bupropion minimally altered CYP2E1 protein (1.2 fold).	Bupropion	77-86	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	105-111	
17697034-0	2007	Is bupropion a more specific substrate for porcine CYP2E than chlorzoxazone and p-nitrophenol?	Bupropion	3-12	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	51-56	
17697034-5	2007	Incubation with bupropion concentrations ranging from 0.05 to 20 mM and with various inhibitors revealed that this substrate is metabolized by both CYP2A and CYP2E.	Bupropion	16-25	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	158-163	
17697034-9	2007	Furthermore, bupropion is a more specific substrate for CYP2E than chlorzoxazone and p-nitrophenol although not perfect.	Bupropion	13-22	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	56-61	
10997944-6	2000	Among a panel of cDNA-expressed P450 isoforms, CYP2B6 and CYP2E1 demonstrated the highest rates of BUP hydroxylation at 12 mM BUP (7.0 and 2.4 pmol/min/pmol of P450, respectively).	Bupropion	99-102	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	58-64