PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22859721-0	2012	In silico and intuitive predictions of CYP46A1 inhibition by marketed drugs with subsequent enzyme crystallization in complex with fluvoxamine.	Fluvoxamine	131-142	cytochrome P450 family 46 subfamily A member 1	Homo sapiens	39-46	
22859721-5	2012	One of the identified tight binders, the widely used antidepressant fluvoxamine, was cocrystallized with CYP46A1.	Fluvoxamine	68-79	cytochrome P450 family 46 subfamily A member 1	Homo sapiens	105-112	
22859721-7	2012	The NH(2)-containing arm of the Y-shaped fluvoxamine coordinates the CYP46A1 heme iron, whereas the methoxy-containing arm points away from the heme group and has multiple hydrophobic interactions with aliphatic amino acid residues.	Fluvoxamine	41-52	cytochrome P450 family 46 subfamily A member 1	Homo sapiens	69-76